1 Result for "

PEX5-PEX14 PPI-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PEX5-PEX14 PPI-IN-4" in MCE Product Catalog:

Cat. No.: HY-182443
CAS No.: 1884470-47-6
Target:  

Parasite

Research Areas:  

Infection

PEX5-PEX14 PPI-IN-4 is a potent PEX14-PEX5 PPI inhibitor, with EC50 values of 7.78 μM, 27.5 μM and 9.31 μM against the protein-protein interactions of TbPEX14-PEX5, TcPEX14-PEX5 and HsPEX14-PEX5, respectively. PEX5-PEX14 PPI-IN-4 exhibits trypanocidal activity against Trypanosoma brucei rhodesiense and Trypanosoma cruzi. PEX5-PEX14 PPI-IN-4 shows cytotoxic activity against mammalian cells. PEX5-PEX14 PPI-IN-4 can be used in the research of human African trypanosomiasis and Chagas disease .
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