1 Result for "

PKM2/PDK1-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PKM2/PDK1-IN-1" in MCE Product Catalog:

Cat. No.: HY-149275
CAS No.: 3041957-90-5
Research Areas:  

Cancer

PKM2/PDK1-IN-1, one of shikonin thioether derivatives, is a dual inhibitor of PKM2/PDK1. PKM2/PDK1-IN-1 inhibits the proliferation of NSCLC cells, and induces apoptosis. PKM2/PDK1-IN-1 induces intercellular ROS production, and regulates the apoptotic proteins, to involves in mitochondrial and death receptor pathway .
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