2 Results for "

PKMYT1-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PKMYT1-IN-4" in MCE Product Catalog:

Cat. No.: HY-162986
CAS No.: 3047617-07-9
Target:  

Wee1

Research Areas:  

Cancer

PKMYT1-IN-4 (compund 27) is a PKMYT1 inhibitor with IC50 less than 50 nM .
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Cat. No.: HY-183547
CAS No.: 3055032-68-0
Target:  

Wee1 CDK

Research Areas:  

Cancer

WEE1/PKMYT1-IN-4 is a selective WEE1/PKMYT1 inhibitor, with IC50 values of 0.185 μM and 2.2 nM for human WEE1 and PKMYT1, respectively. WEE1/PKMYT1-IN-4 inhibits phosphorylation of CDK1 at T14 and Y15, disrupting the G2/M cell cycle checkpoint. WEE1/PKMYT1-IN-4 can be used for the research of colorectal cancer and amplified breast cancer .
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