1 Result for "

PNU 183792

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PNU 183792" in MCE Product Catalog:

Cat. No.: HY-148852
CAS No.: 282536-25-8
Target:  

HSV

Research Areas:  

Infection

PNU-183792, a 4-oxo-dihydroquinoline, is an orally active HSV polymerases inhibitor. PNU-183792 shows a broad-spectrum antiviral activity, with IC50 values of 0.69 μM, 0.37 μM and 0.58 μM for human cytomegalovirus (HCM), varicella zoster virus and HSV polymerases, respectively. PNU-183792 is inactive against human α, γ and δ polymerases. PNU-183792 also inhibits simian varicella virus (SVV), murine cytomegalovirus (MCMV) and rat cytomegalovirus (RCMV) .
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