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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
PROTAC BRD4 Degrader-32
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "PROTAC BRD4 Degrader-32" in MCE Product Catalog:
Cat. No.: HY-176449
Target:
Research Areas:
PROTAC BRD4 Degrader-32 is a CRBN-recruiting PROTAC degrader targeting BRD4 (DC50=0.2 nM in HEK293 cells). PROTAC BRD4 Degrader-32 exhibits an IC50 of 0.05 μM against human CRBN and an IC50 of 22 nM against human BRD4. PROTAC BRD4 Degrader-32 induces reduced degradation of CK1α and WIZ, causes low-level degradation of IKZF1, and does not regulate GSPT1. PROTAC BRD4 Degrader-32 holds promise for research on BRD4-related cancers (such as hematological malignancies) .
Cat. No.: HY-176450
CAS No.: 100401-28-3
Target:
Research Areas:
4-Aminobutyl 4-methylbenzenesulfonate is a PROTAC linker. 4-Aminobutyl 4-methylbenzenesulfonate can be used to synthesize PROTACs, such as PROTAC BRD4 Degrader-32 (HY-176449) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
