2 Results for "

PROTAC BRD4 Degrader-41

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PROTAC BRD4 Degrader-41" in MCE Product Catalog:

Cat. No.: HY-179734
Research Areas:  

Cancer

PROTAC BRD4 Degrader-41 (Compound A5) is a BRD4 PROTAC degrader with a DC50 of 0.97 nM. PROTAC BRD4 Degrader-41 exhibits potent anti-proliferative activity against various types of cancer cells such as AML, lymphoma, breast cancer, ovarian cancer, and non-small cell lung cancer. PROTAC BRD4 Degrader-41 can induce G0/G1 phase arrest and apoptosis in MV4-11 cells. PROTAC BRD4 Degrader-41 downregulates the transcriptional level of c-Myc .
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Cat. No.: HY-179735
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

CRBN ligand-192 is an E3 ligand that can be used for the synthesis of PROTACs, such as PROTAC BRD4 Degrader-41 (HY-179734). PROTAC BRD4 Degrader-41 is a potent BRD4 PROTAC degrader with anti-cancer activity .
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