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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
PROTAC GPX4 degrader-2
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "PROTAC GPX4 degrader-2" in MCE Product Catalog:
Cat. No.: HY-162106
CAS No.: 3035509-76-0
Research Areas:
PROTAC GPX4 degrader-2 is a cIAP-recruiting GPX4 PROTAC degrader with a DC50 of 1.68 μM. PROTAC GPX4 degrader-2 forms a ternary complex with GPX4 and cIAP, and induces GPX4 degradation via the ubiquitin-proteasome system pathway. PROTAC GPX4 degrader-2 induces Mitochondrial depolarization and Ferroptosis. PROTAC GPX4 degrader-2 exhibits antiproliferative effects in cancer cells. PROTAC GPX4 degrader-2 can be used for the research of fibrosarcoma .
Cat. No.: HY-175903
CAS No.: 2700269-62-9
Research Areas:
GPX4 ligand-1 is a GPX4 ligand, which can be used for the synthesis of PROTACs, such as PROTAC GPX4 degrader-2 (HY-162106) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
