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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
PROTAC PTPN2 degrader-1
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "PROTAC PTPN2 degrader-1" in MCE Product Catalog:
Target:
Research Areas:
PROTAC PTPN2 degrader-1 is a PROTAC degrader targeting non-receptor protein tyrosine phosphatase 2 (PTPN2), with a DC50 of 18 nM in 293T cells. It exhibits an IC50 of 22 nM against PTPN2. Through highly selective degradation and inhibition of PTPN2 phosphatase, PROTAC PTPN2 degrader-1 relieves the negative regulation of the IFNγ pathway, upregulates interferon signaling, activates effector T cells, and enhances anti-tumor immunity. PROTAC PTPN2 degrader-1 can be used in melanoma-related research .
Cat. No.: HY-W585105
CAS No.: 2652033-78-6
Research Areas:
PTPN2 ligand 3 is the target protein ligand of PROTAC PTPN2 degrader-1 (HY-148691). PROTAC PTPN2 degrader-1 is a PROTAC degrader that targets non-receptor protein tyrosine phosphatase 2 (PTPN2) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
