1 Result for "

PROTAC c-Met Degrader-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTAC c-Met Degrader-4" in MCE Product Catalog:

Cat. No.: HY-171824
CAS No.: 2959535-15-8
Research Areas:  

Cancer

PROTAC c-Met Degrader-4 (compound D15) is a potent orally active PROTAC c-MET degrader. PROTAC c-Met Degrader-4 demonstrates excellent intracellular degradation potency with a DC50 < 0.5 nM. PROTAC c-Met Degrader-4 induces cell cycle arrest and apoptosis, inhibits cell invasion and migration, thereby suppressing cell proliferation. PROTAC c-Met Degrader-4 inhibits the growth of Hs746T xenograft tumors in nude mice. PROTAC c-Met Degrader-4 can be used for cancer research, such as non-small cell lung cancer and gastric cancer .
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