1 Result for "

Paclitaxel-bromothiophene

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Paclitaxel-bromothiophene" in MCE Product Catalog:

Cat. No.: HY-175981
Target:  

Drug Derivative

Research Areas:  

Cancer

Paclitaxel-bromothiophene is a semisynthetic taxane analogue of Paclitaxel (HY-B0015). Paclitaxel-bromothiophene exhibits potent antiproliferative activity against 4-T1 breast cancer cells, with an IC50 value of 15.18 nM. Paclitaxel-bromothiophene shows high binding affinity to C5aR1 (Kd = 19.4 μM). Paclitaxel-bromothiophene demonstrates excellent anti-tumor efficacy in 4-T1 breast cancer-bearing mice. Paclitaxel-bromothiophene can be used for the study of breast cancer .
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