2 Results for "

Pestalotiopsis microspora

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Pestalotiopsis microspora" in MCE Product Catalog:

7-Epi 10-desacetyl paclitaxel
7-Epi 10-desacetyl paclitaxel
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Cat. No.: HY-77572
CAS No.: 78454-17-8
Synonyms: 7-epi-10-deacetyltaxol; 10-Deacetyl-7-epipaclitaxel
Category:  

Microorganisms Terpenoids Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.

Target:  

Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Bcl-2 Family PARP

7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol; 10-Deacetyl-7-epipaclitaxel) is a taxane diterpenoid that can be found in Taxus species and is also produced by the endophytic fungus Pestalotiopsis microspora. 7-Epi 10-desacetyl paclitaxel inhibits cancer cell proliferation and induces apoptosis and cell cycle arrest. 7-Epi 10-desacetyl paclitaxel induces apoptosis through the intrinsic mitochondrial pathway, a process associated with ROS generation, an increased Bax/Bcl-2 ratio, and PARP cleavage. 7-Epi 10-desacetyl paclitaxel can be used in research on hepatocellular carcinoma .
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7-Epi 10-desacetyl paclitaxel (Standard)
7-Epi 10-desacetyl paclitaxel (Standard)
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Cat. No.: HY-77572R
CAS No.: 78454-17-8
Synonyms: 7-epi-10-deacetyltaxol (Standard); 10-Deacetyl-7-epipaclitaxel (Standard)
Category:  

Microorganisms Terpenoids Taxaceae Diterpenoids Plants Taxus chinensis (Pilger) Rehd.

Target:  

Reference Standards Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Bcl-2 Family PARP

7-Epi 10-desacetyl paclitaxel (Standard) (7-epi-10-deacetyltaxol (Standard); 10-Deacetyl-7-epipaclitaxel (Standard)) is the analytical standard of 7-Epi 10-desacetyl paclitaxel (HY-77572). This product is intended for research and analytical applications. 7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol; 10-Deacetyl-7-epipaclitaxel) is a taxane diterpenoid that can be found in Taxus species and is also produced by the endophytic fungus Pestalotiopsis microspora. 7-Epi 10-desacetyl paclitaxel inhibits cancer cell proliferation and induces apoptosis and cell cycle arrest. 7-Epi 10-desacetyl paclitaxel induces apoptosis through the intrinsic mitochondrial pathway, a process associated with ROS generation, an increased Bax/Bcl-2 ratio, and PARP cleavage. 7-Epi 10-desacetyl paclitaxel can be used in research on hepatocellular carcinoma .
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