109 Results for "

Porphyrin

" in MedChemExpress (MCE) Product Catalog:
Products (109)

109 Results for "Porphyrin" in MCE Product Catalog:

94
94 Publications Verification
Cat. No.: HY-19424
CAS No.: 16009-13-5
Synonyms: Hemin chloride
Hemin is an iron-containing porphyrin. Hemin is an Heme oxygenase (HO)-1 inducer.
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-16488
CAS No.: 122341-38-2
Synonyms: m-THPC; KW2345
Research Areas:  

Cancer

Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-126397
CAS No.: 55266-18-7
Purity:  ≥98.0%
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology

MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects through upregulation of BMPR-II and inhibition of the NFκB signaling. MnTBAP chloride has the potential for the fibrotic response in chronic kidney diseases (CKDs) research .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-137808
CAS No.: 108347-97-3
Purity:  94%
Synonyms: Succinyl-CoA sodium
Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-101398
CAS No.: 14643-66-4
Purity:  99.57%
Synonyms: Zincphyrin
Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-W412175
CAS No.: 68938-73-8
Synonyms: Zincphyrin dihydrochloride
Research Areas:  

Infection

Coproporphyrin III dihydrochloride (Zincphyrin dihydrochlorid) is a naturally occurring porphyrin derivative that is mainly found in urine .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-134990
CAS No.: 148471-91-4
Purity:  ≥95.0%
Target:  

Apoptosis

Research Areas:  

Cancer

Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and research of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W075707
CAS No.: 55266-17-6
Synonyms: Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride
FeTCPP chloride (Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride) is a metallic porphyrin compound formed by the coordination of a central iron ion (Fe 3+) with four 4-carboxyphenylporphyrins (TCPP). FeTCPP chloride can be used as a catalyst for catalytic, electrochemical, photochemical and biomedical research. FeTCPP chloride has high photocatalytic performance for p-nitrophenol under visible light. FeTCPP chloride also has peroxisase-like activity, which is used in bionic catalysis research .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W040030
CAS No.: 15489-90-4
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease Cancer

Hematin, an iron-containing porphyrin, inhibits the activity of clotting factors and also fibrin clot lysis through the mechanism of binding to and inactivation of hemostatic proteins . Hematin can be used for the research of acute porphyrias and cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W008852
CAS No.: 14609-54-2
Synonyms: TCPP
Target:  

MOFs

Research Areas:  

Others

Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-131697
CAS No.: 90384-82-0
Purity:  99.00%
Target:  

MOFs NO Synthase Apoptosis

Research Areas:  

Inflammation/Immunology

FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage . FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-A0169A
CAS No.: 79416-27-6
Research Areas:  

Cancer

Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .
loading...
    loading...
Cat. No.: HY-W073080
CAS No.: 69477-27-6
Coproporphyrin I dihydrochlorideIt is an organic compound belonging to the class of porphyrins. It is a derivative of heme, an iron-containing molecule found in hemoglobin and other proteins. Coproporphyrin I dihydrochlorideOften used as a biomarker in the assessment of certain liver and metabolic diseases, especially those related to bile synthesis and transport. It can also be used as a reference standard for analytical chemistry and pharmacological research.
loading...
    loading...
Cat. No.: HY-16045
CAS No.: 140898-91-5
Synonyms: Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours .
loading...
    loading...
Cat. No.: HY-103656
CAS No.: 917-23-7
Purity:  99.43%
Synonyms: TPP; Tetraphenylporphine; meso-TetraphenylPorphyrin
Target:  

MOFs

Research Areas:  

Cancer

Tetraphenylporphyrin (TPP) is a symmetrically substituted porphyrin-based heterocyclic compound and used as a structural block for supramolecular synthesis. Tetraphenylporphyrin derivatives can be used for cancer research .
loading...
    loading...
Cat. No.: HY-130574
CAS No.: 219818-60-7
Purity:  ≥95.0%
Synonyms: BMX-010 chloride
Research Areas:  

Cancer

MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer .
loading...
    loading...
Cat. No.: HY-W035138
CAS No.: 29162-73-0
Tetra(p-bromophenyl)porphyrin (compound 5c) is a fluorescent dye. Tetra(p-bromophenyl)porphyrin can be used for the synthesis of perfuoroalkyl-substituted tetrakisphenylporphyrins .
loading...
    loading...
Cat. No.: HY-P2888
CAS No.: 80619-01-8
Synonyms: BOD
Research Areas:  

Metabolic Disease

Bilirubin oxidase (BOD) is an electrocatalyst with oxygen removal activity. Bilirubin oxidase can catalyze the oxidation of bilirubin to biliverdin. Bilirubin oxidase participates in the metabolism of porphyrins and chlorophyll, and acts as a catalyst for oxygen reduction. Bilirubin oxidase can serve as a component of a single-enzyme oxygen removal system for reductase-based voltammetric biosensors .
loading...
    loading...
Cat. No.: HY-W035136
CAS No.: 22112-84-1
Target:  

Endogenous Metabolite

Research Areas:  

Others

Meso-tetrakis(4-aminophenyl)porphyrin (IV) is a porphyrin derivative .
loading...
    loading...
Cat. No.: HY-W075425
CAS No.: 40904-90-3
Synonyms: meso-Tetrakis(2-pyridyl)porphine
5,10,15,20-Tetra(pyridin-2-yl)porphyrin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
loading...
    loading...