1. Immunology/Inflammation Apoptosis
  2. NO Synthase Apoptosis
  3. FeTPPS

FeTPPS 

Cat. No.: HY-131697 Purity: ≥95.0%
COA Handling Instructions

FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process.

For research use only. We do not sell to patients.

FeTPPS Chemical Structure

FeTPPS Chemical Structure

CAS No. : 90384-82-0

Size Price Stock Quantity
5 mg USD 38 In-stock
10 mg USD 60 In-stock
25 mg USD 110 In-stock
50 mg USD 180 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage[1]. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process[2].

In Vitro

FeTPPS acts as an effective pro-oxidant towards appreciable substrates in vitro in the presence of oxidant. FeTPPS protects cells against oxidative damage induced by H2O2, generated by Glucose (G)-glucose oxidase (GO) system[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[2]

Cell Line: Human hepatocellular carcinoma (HepG2)
Concentration: 5, 10, 15, 20, 25 μM
Incubation Time: Treated 12 h before being exposed to H2O2
Result: Could protect cells against oxidative damage induced by H2O2.
Molecular Weight

1024.27

Formula

C44H28ClFeN4O12S4

CAS No.
Appearance

Solid

Color

Brown to black

SMILES

O=S([O-])(C1=CC=C(C(C(C=C2)=[N]3C2=C(C4=CC=C5C(C6=CC=C(S(=O)([O-])=O)C=C6)=C7C=C8)C9=CC=C(S(=O)([O-])=O)C=C9)=C%10C=CC%11=C(C%12=CC=C(S(=O)([O-])=O)C=C%12)C8=[N]7[Fe+3]3([Cl-])([N-]45)[N-]%10%11)C=C1)=O.[4H+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (9.76 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9763 mL 4.8815 mL 9.7631 mL
5 mM 0.1953 mL 0.9763 mL 1.9526 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: ≥95.0%

References
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FeTPPS Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
FeTPPS
Cat. No.:
HY-131697
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