1 Result for "

RASopathies

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RASopathies" in MCE Product Catalog:

Cat. No.: HY-187882
CAS No.: 3079099-31-0
Synonyms: PAS-004
Target:  

MEK PERK

Research Areas:  

Cancer

Nuvrumetinib (PAS-004) is a macrocyclic MEK inhibitor. Nuvrumetinib functionally inhibits MEK1/2, thereby suppressing pERK in tumors. Nuvrumetinib inhibits the proliferation of NRAS-mutant cancer cells. Nuvrumetinib can be used in studies related to NRAS G12C-mutant solid tumors, neurofibromatosis type 1 (NF1), RASopathies and laminopathies .
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