1 Result for "

RORγ antagonist 1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RORγ antagonist 1" in MCE Product Catalog:

Cat. No.: HY-155542
CAS No.: 3049676-15-2
Target:  

ROR

Research Areas:  

Cancer

RORγ antagonist 1 (compound 22), a potent betulinic acid derivative, is an antagonist of RORγ (KD=0.18 μM). RORγ antagonist 1 exhibits anti-proliferative activity in HPAF-II pancreatic cancer xenograft model. RORγ antagonist 1 inhibits RAS/MAPK and AKT/mTORC1 pathway, and induces caspase-dependent apoptosis in pancreatic cancer cells .
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