1 Result for "

RORγt Inverse agonist 10

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RORγt Inverse agonist 10" in MCE Product Catalog:

Cat. No.: HY-133552
CAS No.: 2413986-35-1
Purity:  99.13%
Target:  

ROR

Research Areas:  

Inflammation/Immunology

RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R
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