2 Results for "

RORγt agonist 3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RORγt agonist 3" in MCE Product Catalog:

Cat. No.: HY-142938
CAS No.: 2664106-24-3
Purity:  98.12%
Target:  

ROR

Research Areas:  

Inflammation/Immunology Cancer

RORγt agonist 3 is a potent agonist of RORγt. RORγt agonist 3 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 3 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136326A1, compound 23) .
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Cat. No.: HY-128573
CAS No.: 2364429-77-4
Purity:  99.93%
Target:  

ROR

Research Areas:  

Neurological Disease

RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively .
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