1. Metabolic Enzyme/Protease
  2. ROR
  3. RORγt Inverse agonist 3

RORγt Inverse agonist 3 

Cat. No.: HY-128573
Handling Instructions

RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively.

For research use only. We do not sell to patients.

RORγt Inverse agonist 3 Chemical Structure

RORγt Inverse agonist 3 Chemical Structure

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Description

RORγt Inverse agonist 3 is a potent, selective and orally active RORγ inverse agonist, with EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively[1].

IC50 & Target

EC50: 0.22 μM (hRORγ), 0.15 μM (RORγt, human IL-17 cells)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

616.56

Formula

C₂₉H₃₁Cl₂N₅O₄S

SMILES

CC(C)C1=NC2=C(C=CC=C2OCC3=C(Cl)C=CC(S(=O)(N4CCC[[email protected]]4C(NC)=O)=O)=C3Cl)C(C5=CN=CN5C)=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
RORγt Inverse agonist 3
Cat. No.:
HY-128573
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RORγt Inverse agonist 3

Cat. No.: HY-128573