2 Results for "

Reduced scytonemin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Reduced scytonemin" in MCE Product Catalog:

Scytonemin
Scytonemin
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Cat. No.: HY-112356
CAS No.: 152075-98-4
Purity:  99.53%
Category:  

Alkaloids Microorganisms Sunscreen Cosmetic Research Indole Alkaloids

Target:  

Apoptosis Reactive Oxygen Species (ROS) Polo-like Kinase (PLK)

Scytonemin is a hydrophobic alkaloid pigment that can be isolated from the outer sheath of cyanobacteria. Scytonemin has protective function against short-wave solar ultraviolet (UV) radiation, which can reduce the generation of reactive oxygen species (ROS) and the formation of DNA damage. Scytonemin also has anti-inflammatory and anti-proliferative activities, produces concentration-dependent inhibition (IC50=2.0 μM) of polo-like kinase 1 (PLK1)-mediated cdc25C phosphorylation, and plays an important role in regulating the G2/M transition in the cell cycle. It can be used in the research of cancer, acute inflammation and sunscreen cosmetics .
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JRN73958
JRN73958
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Cat. No.: HY-182236
CAS No.: 171773-95-8
Synonyms: Reduced scytonemin
Category:  

Alkaloids Microorganisms Other Alkaloids

Target:  

PI3K p38 MAPK NF-κB NO Synthase Reactive Oxygen Species (ROS) Autophagy

JRN73958 (Reduced scytonemin) is a PI3K/Akt, MAPK, and NF-κB inhibitor found in Nostoc commune. JRN73958 inhibits nitric oxide production, induce reactive oxygen species (ROS) generation, and lead to autophagy. JRN73958 decreases LPS (HY-D1056)/IFNγ-induced PI3K/Akt, MAPK, and NF-κB activity. JRN73958 can be used for the research of leukemia .
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