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3 Results for "
Ro 44-3888
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "Ro 44-3888" in MCE Product Catalog:
Cat. No.: HY-187608
CAS No.: 144412-18-0
Target:
Research Areas:
Ro 44-3888 is an orally active and selective GP IIb-IIIa (fibrinogen receptor, integrin αIIbβ3) inhibitor with an IC50 of 1.9 nM against the human target. Ro 44-3888 blocks the binding of fibrinogen to GP IIb-IIIa and inhibits human ADP-induced platelet aggregation. Ro 44‑3888 is formed via the metabolism of the double prodrug Ro 48‑3657 (HY-10309). Ro 44-3888 is used in studies related to arterial thrombosis .
Synonyms: Ro 48-3657
Target:
Research Areas:
Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
Cat. No.: HY-10309R
CAS No.: 172927-65-0
Synonyms: Ro 48-3657 (Standard)
Target:
Research Areas:
Sibrafiban (Standard) is the analytical standard of Sibrafiban. This product is intended for research and analytical applications. Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
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