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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
SARS-CoV-2 Mpro-IN-4
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "SARS-CoV-2 Mpro-IN-4" in MCE Product Catalog:
Cat. No.: HY-151900
Target:
Research Areas:
SARS-CoV-2 Mpro-IN-4 is a dual Inhibitor of Main Protease (M Pro) and Cathepsin L (CatL), with IC50s of 900 nM and 60 nM respectively. SARS-CoV-2 Mpro-IN-4 has antiviral activity against SARS-CoV2. SARS-CoV-2 Mpro-IN-4 blocks SARS-CoV2 replication in hACE2 expressing A549 cells with IC50 value of 8.2 nM .
Cat. No.: HY-174233
Target:
Research Areas:
PROTAC SARS-CoV-2 Mpro degrader-4 is a SARS-CoV-2 M Pro PROTAC degrader with antiviral activity, with a DC50 value of 4.7 μM. PROTAC SARS-CoV-2 Mpro degrader-4 induces M Pro ubiquitination and proteasomal degradation, and inhibits SARS-CoV-2 replication. PROTAC SARS-CoV-2 Mpro degrader-4 can be used in the research of coronavirus infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
