1 Result for "

SIRT6-IN-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SIRT6-IN-6" in MCE Product Catalog:

Cat. No.: HY-16605
CAS No.: 23491-48-7
Target:  

Sirtuin GLUT

Research Areas:  

Metabolic Disease

SIRT6-IN-6 (compound 6d) is a potent and selective SIRT6 inhibitor with an IC50 of 4.93 μM and a Ki of ~10 μM. SIRT6-IN-6 shows selectivity against other members of the HDAC family (SIRT1-3 and HDAC1-11). SIRT6-IN-6 significantly increases the level of glucose transporter GLUT-1, thereby reducing blood glucose in a mouse model of type 2 diabetes. SIRT6-IN-6 can be used for type 2 diabetes research .
loading...
    loading...