Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
STAT6-IN-6
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "STAT6-IN-6" in MCE Product Catalog:
Cat. No.: HY-164203
CAS No.: 2952725-20-9
STAT6-IN-6 (compound 163) is a selective STAT6 inhibitor. STAT6-IN-6 selectively inhibits STAT6 phosphorylation, with IC50s of ≤100nM and >3μM for pSTAT6 and pSTAT3, respectively. STAT6-IN-6 can be used for the study of cancer and inflammatory diseases .
Target:
Research Areas:
STAT6-IN-2 (Compound R-84) is a STAT6 inhibitor that can inhibit the tyrosine phosphorylation of STAT6. STAT6-IN-2 can also inhibit the secretion of eotaxin-3. STAT6-IN-2 can be used in the research of immune diseases and allergic inflammatory diseases such as asthma .
Cat. No.: HY-176864
Research Areas:
STAT6 ligand-1 is a ligand for STAT6. STAT6 ligand-1 can be used for synthesizing PROTACs such as STAT6 degrader-2 (HY-176857) .
Synonyms: NCX 4016
Target:
Research Areas:
Nitroaspirin (NCX 4016) is an orally active inhibitor of ARG1 and NOS2. Nitroaspirin reduces ARG1 enzymatic activity via the STAT6-mediated signaling pathway, and feedback-inhibits the catalytic activity of NOS2 in a NO-releasing group-dependent manner. Nitroaspirin continuously releases intracellular NO, inducing redox-dependent loss of cell viability. Nitroaspirin also exerts anti-angiogenic effects by causing endothelial barrier dysfunction, and effectively inhibits the proliferation of Cisplatin (HY-17394)-resistant human ovarian cancer cells . Nitroaspirin can be used in research related to colon cancer, breast cancer and Cisplatin-resistant human ovarian cancer .
Cat. No.: HY-180475
Research Areas:
STAT6 ligand-1 is a ligand of STAT6. STAT6 ligand-1 can be used to synthesize PROTACs, such as Compound 22 .
Cat. No.: HY-171441
CAS No.: 3063673-73-1
Target:
Research Areas:
STAT6 degrader-1 (Compound 21) is a bifunctional molecular glue degrader of STAT6 that recruits E3 ubiquitin ligase. STAT6 degrader-1 induces proteasomal degradation of STAT6. STAT6 degrader-1 is applicable to the research of cancer, inflammatory diseases and colorectal cancer .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
