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STAT6-IN-6

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153991
    STAT6-IN-2

    		STAT Inflammation/Immunology
    STAT6-IN-2 (Compound R-84) is a STAT6 inhibitor that can inhibit the tyrosine phosphorylation of STAT6. STAT6-IN-2 can also inhibit the secretion of eotaxin-3. STAT6-IN-2 can be used in the research of immune diseases and allergic inflammatory diseases such as asthma .
    STAT6-IN-2
  • HY-164203
    STAT6-IN-6

    		STAT Cancer
    STAT6-IN-6 (compound 163) is a selective STAT6 inhibitor. STAT6-IN-6 selectively inhibits STAT6 phosphorylation, with IC50s of ≤100nM and >3μM for pSTAT6 and pSTAT3, respectively. STAT6-IN-6 can be used for the study of cancer and inflammatory diseases .
    STAT6-IN-6
  • HY-176864
    STAT6 ligand-1

    		Ligands for Target Protein for PROTAC STAT Inflammation/Immunology Cancer
    STAT6 ligand-1 is a ligand for STAT6. STAT6 ligand-1 can be used for synthesizing PROTACs such as STAT6 degrader-2 (HY-176857) .
    STAT6 ligand-1
  • HY-W1113770
    STAT6-IN-8

    		STAT Inflammation/Immunology
    STAT6-IN-8 (Compound 9) is a STAT6 inhibitor with potential anti-inflammatory and anti-allergic effects. STAT6-IN-8 can be used for the study of STAT6-associated diseases, including inflammatory diseases (atopic dermatitis, bronchial asthma) and allergic diseases (allergic rhinitis, chronic sinusitis) .
    STAT6-IN-8
  • HY-179233
    PROTAC STAT6 degrader-2

    		PROTACs STAT Cancer
    PROTAC STAT6 degrader-2 is a highly efficient PROTAC degrader targeting STAT6. PROTAC STAT6 degrader-2 has a DC50 value of 1-10 nM for STAT6 in human PBMC cells and a DC50 value of less than 100 nM for STAT6 in HEK293-HIBiT-STAT6 cells. PROTAC STAT6 degrader-2 can be used for STAT6-mediated diseases .
    PROTAC STAT6 degrader-2
  • HY-180475
    STAT6 ligand-2

    		Ligands for Target Protein for PROTAC STAT Cancer
    STAT6 ligand-1 is a ligand of STAT6. STAT6 ligand-1 can be used to synthesize PROTACs, such as Compound 22 .
    STAT6 ligand-2
  • HY-171441
    STAT6 degrader-1

    		STAT Inflammation/Immunology Cancer
    STAT6 degrader-1 (Compound 21) is a bifunctional molecular glue degrader of STAT6 that recruits E3 ubiquitin ligase. STAT6 degrader-1 induces proteasomal degradation of STAT6. STAT6 degrader-1 is applicable to the research of cancer, inflammatory diseases and colorectal cancer .
    STAT6 degrader-1

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