3063673-73-1
Chemical Structure
STAT6 degrader-1
- CAS No.: 3063673-73-1
- Formula:C67H78F2N7O13PS2
- Molecular Weight:1322.48
InChIKey: CGTDSZZZTHPDOU-JTQXEHBSSA-N
SMILES: O=C([C@H]1N2[C@](CCN(C[C@@H](C2=O)NC(C3=CC4=C(C=CC(C(F)(F)P(OCCSC(CC(C)C)=O)(OCCSC(CC(C)C)=O)=O)=C4)C=C3)=O)C(C(C5=C6)=NOC5=CC=C6C)=O)([H])CC1)N(C)CCCCCCC#CC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=CC=C7
Biological Activity: STAT6 degrader-1 (Compound 21) is a bifunctional molecular glue degrader of STAT6 that recruits E3 ubiquitin ligase. STAT6 degrader-1 induces proteasomal degradation of STAT6. STAT6 degrader-1 is applicable to the research of cancer, inflammatory diseases and colorectal cancer[1].
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STAT6 degrader-1 | STAT6 degrader-1 (Compound 21) is a bifunctional molecular glue degrader of STAT6 that recruits E3 ubiquitin ligase. STAT6 degrader-1 induces proteasomal degradation of STAT6. STAT6 degrader-1 is applicable to the research of cancer, inflammatory diseases and colorectal cancer. | |||||||||||||||||||||
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Keywords
