2. PROTAC Stem Cell/Wnt JAK/STAT Signaling
  3. Ligands for Target Protein for PROTAC STAT
  4. STAT6 ligand-1

STAT6 ligand-1 is a ligand for STAT6. STAT6 ligand-1 can be used for synthesizing PROTACs such as STAT6 degrader-2 (HY-176857).

For research use only. We do not sell to patients.

STAT6 ligand-1

STAT6 ligand-1 Chemical Structure

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

STAT6 ligand-1 Related Antibodies

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STAT3 STAT5 STAT6 STAT1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

STAT6 ligand-1 is a ligand for STAT6. STAT6 ligand-1 can be used for synthesizing PROTACs such as STAT6 degrader-2 (HY-176857)[1].

IC50 & Target[1]

STAT6

 

Molecular Weight

426.90

Formula

C21H23ClN6O2
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC2=C(C=C(C=C2N1)C3=CCCN(C3)C(CCN4N=NC=C4)=O)Cl)N(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (234.25 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3425 mL 11.7123 mL 23.4247 mL
5 mM 0.4685 mL 2.3425 mL 4.6849 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3425 mL 11.7123 mL 23.4247 mL 58.5617 mL
5 mM 0.4685 mL 2.3425 mL 4.6849 mL 11.7123 mL
10 mM 0.2342 mL 1.1712 mL 2.3425 mL 5.8562 mL
15 mM 0.1562 mL 0.7808 mL 1.5616 mL 3.9041 mL
20 mM 0.1171 mL 0.5856 mL 1.1712 mL 2.9281 mL
25 mM 0.0937 mL 0.4685 mL 0.9370 mL 2.3425 mL
30 mM 0.0781 mL 0.3904 mL 0.7808 mL 1.9521 mL
40 mM 0.0586 mL 0.2928 mL 0.5856 mL 1.4640 mL
50 mM 0.0468 mL 0.2342 mL 0.4685 mL 1.1712 mL
60 mM 0.0390 mL 0.1952 mL 0.3904 mL 0.9760 mL
80 mM 0.0293 mL 0.1464 mL 0.2928 mL 0.7320 mL
100 mM 0.0234 mL 0.1171 mL 0.2342 mL 0.5856 mL
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STAT6 ligand-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STAT6 ligand-1Ligands for Target Protein for PROTACSTATTarget Protein-binding MoietySTAT6PROTACInhibitorinhibitorinhibit

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