1 Result for "

Shank3 TG mice

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Shank3 TG mice" in MCE Product Catalog:

Cat. No.: HY-163345
CAS No.: 1448808-50-1
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

5-HT7R antagonist 2 (compound 4h) is a 5-HT7R antagonist that antagonizes the G protein and β-arrestin signaling pathways, with a Ki of 67 nM, the IC50 values in cAMP and Tango tests were 2.59 μM and 39.57 μM, respectively. 5-HT7R antagonist 2 has an effect on neurogenesis and can reduce repetitive behaviors related to autism spectrum disorder (ASD) and restore neurogenesis of ASD impairment .
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