1 Result for "

Simridarlimab

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Simridarlimab" in MCE Product Catalog:

Cat. No.: HY-P99903
CAS No.: 2378862-90-7
Synonyms: IBI-322

Target:  

PD-1/PD-L1 CD47

Research Areas:  

Inflammation/Immunology Cancer

Simridarlimab (IBI-322) is a bispecific antibody targeting PD-L1 and CD47. Simridarlimab attenuates CD47 activity in monovalent binding and blockes PD-L1 activity in bivalent binding. Simridarlimab selectively binds to CD47+PD-L1+ tumor cells, effectively inhibits CD47-SIRPα signal and triggered strong tumor cell phagocytosis in vitro .
loading...
    loading...