2 Results for "

T338C Src-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "T338C Src-IN-1" in MCE Product Catalog:

Cat. No.: HY-16905
CAS No.: 1351926-90-3
Target:  

Src

Research Areas:  

Cancer

T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
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Cat. No.: HY-16906
CAS No.: 1351927-00-8
Target:  

Src

Research Areas:  

Cancer

T338C Src-IN-2 is a mutant c-Src kinase inhibitor, with an IC50 of 317 nM against T338C c-Src, 57 nM against T338C/V323A c-Src, and 19 nM against T338C/V323S c-Src. T338C Src-IN-2 inhibits the kinase activity of endogenous cysteine gatekeeper MOK. T338C Src-IN-2 reduces global phosphotyrosine levels in v-Src-ES1-transformed NIH-3T3 cells [1].
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