1 Result for "

TQ 416

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TQ 416" in MCE Product Catalog:

Cat. No.: HY-188139
CAS No.: 950388-70-2
Target:  

Apoptosis

Research Areas:  

Infection

TQ416 is a non-competitive inhibitor of paraoxonase 2 (PON2) with an IC50 of 0.775 μM for PON2. TQ416 inhibits PON2 lactonase activity, blocking PON2-dependent 3OC12HSL hydrolysis and intracellular acidification, thereby modulating mitochondrial function, Ca 2+, apoptosis, and cell cycle-related responses. TQ416 is useful for research on PON2 biology and bacterial quorum sensing-related host responses .
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