1 Result for "

TREK inhibitor3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TREK inhibitor3" in MCE Product Catalog:

Cat. No.: HY-172455
CAS No.: 3023854-95-4
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

TREK inhibitor-3 (Cpd8l) is a selective and BBB-permeable TREK-1 inhibitor with an IC50 of 0.81 μM. TREK inhibitor-3 has neuroprotective effects, which can significantly reduce the death of cortical neurons induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and improve brain injury in mice models of middle cerebral artery occlusion/reperfusion (MCAO/R). TREK inhibitor-3 can be used in the research of ischemic stroke .
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