TREK inhibitor-3
TREK inhibitor-3 (Cpd8l) is a selective and BBB-permeable TREK-1 inhibitor with an IC50 of 0.81 μM. TREK inhibitor-3 has neuroprotective effects, which can significantly reduce the death of cortical neurons induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and improve brain injury in mice models of middle cerebral artery occlusion/reperfusion (MCAO/R). TREK inhibitor-3 can be used in the research of ischemic stroke.
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- No. CAS: 3023854-95-4
- Fòrmula: C21H23NO2
- Peso molecular:321.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 3023854-95-4
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Peso molecular 321.41
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Fòrmula C21H23NO2
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SMILES
O=C1C2=CC(C3CCNCC3)=CC=C2C(O1)CC4=CC=CC=C4C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TREK inhibitor-3 Related Classifications
HY-172455 Related Classifications
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