TREK inhibitor-3
TREK inhibitor-3 (Cpd8l) is a selective and BBB-permeable TREK-1 inhibitor with an IC50 of 0.81 μM. TREK inhibitor-3 has neuroprotective effects, which can significantly reduce the death of cortical neurons induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and improve brain injury in mice models of middle cerebral artery occlusion/reperfusion (MCAO/R). TREK inhibitor-3 can be used in the research of ischemic stroke.
For research use only. We do not sell to patients.
- CAS No.: 3023854-95-4
- Formula: C21H23NO2
- Molecular Weight:321.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 3023854-95-4
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Molecular Weight 321.41
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Formula C21H23NO2
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SMILES
O=C1C2=CC(C3CCNCC3)=CC=C2C(O1)CC4=CC=CC=C4C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TREK inhibitor-3 Related Classifications
HY-172455 Related Classifications
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