Telomere

By Targets:	Apoptosis (3) Autophagy (1) Biochemical Assay Reagents (1) c-Myc (1) CMV (2) DNA Stain (1) DNA/RNA Synthesis (8) Endogenous Metabolite (1) Ferroptosis (1) Fluorescent Dye (1) G-quadruplex (7) Mitosis (1) Phosphatase (1) Reference Standards (1) Reverse Transcriptase (1) Telomerase (11)
By Research Areas:	Cancer (20) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (2) Metabolic Disease (4) Neurological Disease (3)
Click Chemistry:	Labeling and Fluorescence Imaging (1)
Oligonucleotides:	Guanosine (1) Nucleoside Analogs (1) Antisense Oligonucleotides (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1485

Cycloastragenol 5+ Cited Publications Astramembrangenin; Cyclosieversigenin	Telomerase	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .

HY-18762

6-Thio-2'-Deoxyguanosine 2 Publications Verification 6-thio-dG; β-TGdR	DNA/RNA Synthesis	Cancer
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.

HY-15943

6-TAMRA 1 Publications Verification 6-Carboxytetramethylrhodamine	Fluorescent Dye	Others
6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays .

HY-163573

FANCM-BTR PPI-IN-1	DNA/RNA Synthesis	Cancer
FANCM-BTR PPI-IN-1 (Compound 32) is a FANCM/BTR interaction inhibitor that blocks the localization of FANCM to telomeres. FANCM-BTR PPI-IN-1 exhibits anticancer activity against osteosarcoma .

HY-15523

Braco-19 5 Publications Verification	CMV DNA/RNA Synthesis G-quadruplex	Cancer
Braco-19 is a potent *telomerase/telomere* inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .

HY-137817

BCH001	DNA/RNA Synthesis	Metabolic Disease
BCH001, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging .

HY-12854

Imetelstat GRN163L	Telomerase Apoptosis	Cardiovascular Disease Cancer
Imetelstat (GRN163L) is a 13-mer oligonucleotide and competitive Telomerase inhibitor. Imetelstat binds with high affinity to the template region of the RNA component of human telomerase. Imetelstat induces Apoptosis. Imetelstat is capable of selectively eliminating myelofibrosis hematopoietic stem cells. Imetelstat leads to the loss of a cancer cell's ability to maintain telomere length, resulting in the inhibition of cell proliferation .

HY-15523A

Braco-19 trihydrochloride 5 Publications Verification	DNA/RNA Synthesis CMV	Infection Cancer
Braco-19 trihydrochloride is a potent telomerase/telomere* inhibitor,* preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .

HY-D1668

Biotin-11-dCTP	DNA Stain Reverse Transcriptase	Infection Neurological Disease Cancer
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

HY-135775

BMVC 1 Publications Verification	G-quadruplex Telomerase DNA/RNA Synthesis	Cancer
BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor with an IC₅₀ of ~0.2 μM. BMVC inhibits Taq DNA polymerase with an IC₅₀ of ~2.5 μM. BMVC increases the melting temperature of G4 structure of telomere and accelerates telomere length shortening. Anticancer activities .

HY-145748

SYUIQ-5	G-quadruplex Autophagy c-Myc	Cancer
SYUIQ-5 is a G-quadruplex ligand. SYUIQ-5 stabilizes G-quadruplex and induce senescence. SYUIQ-5 inhibits c-myc gene promoter activity. SYUIQ-5 induces cancer cells autophagy by triggering telomere damage through TRF2 delocalization from telomeres .

HY-W543137

PT-ttpy	G-quadruplex DNA/RNA Synthesis Mitosis	Cancer
Pt-ttpy, a metallo-organic complex and potent G-quadruplex ligand, effectively triggers substantial telomere-related DNA damage in cancer cells by inhibiting telomerase and/or telomere functions, while also causing various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

HY-169120

FKB04	Telomerase	Cancer
FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanism in liver cancer cells, leading to T-loop defects, telomere shortening, and cellular senescence. Additionally, FKB04 can inhibit tumor growth in a human liver cancer xenograft mouse model (with Huh-7 cells implanted in BALB/c mice). FKB04 can be used in liver cancer research .

HY-146812

DIZ-3	G-quadruplex	Cancer
DIZ-3 is a selective multimeric G4 ligand based on a G4-ligand-dimerizing strategy. DIZ-3 intercalates into the G4-G4 interface, stabilizing the higher-order structure. DIZ-3 induces cell cycle arrest and apoptosis, and thus inhibits cell proliferation in alternative lengthening of telomere (ALT) cancer cells .

HY-P11224

RMI-L4	DNA/RNA Synthesis	Cancer
RMI-L4 is an efficient cyclic peptide inhibitor that can specifically disrupt the interaction between FANCM and RMI proteins with an IC₅₀ of 54 nM. RMI-L4 engages the FANCM-binding pocket of RMI1/2 with nanomolar affinity (K_D = 2.5 nM). RMI-L4 cannot penetrate the cell membrane and can be used to study the FANCM-RMI pathway targeting cancer with alternate lengthening of telomeres (ALT) .

HY-N1485R

Cycloastragenol (Standard) Astramembrangenin (Standard); Cyclosieversigenin (Standard)	Reference Standards Telomerase	Neurological Disease Inflammation/Immunology
Cycloastragenol (Standard) is the analytical standard of Cycloastragenol. This product is intended for research and analytical applications. Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .

HY-148200A

L2H2-6OTD diformic	Telomerase	Cancer
L2H2-6OTD acetate contains one to four G-quadruplex binding loops and is a telomere inhibitor analog. L2H2-6OTD acetate has telomerase inhibitory activity with an IC₅₀ value of 15 nM .

HY-153917

CRT0063465	Phosphatase	Metabolic Disease Cancer
CRT0063465 is a Ligand of HumanPGK1andStress Sensor DJ1, with theK_dof 24 μM ofPGK1. CRT0063465 modulates the shelterin complex composition and telomere Length .

HY-169518

TERT activator-2	Telomerase	Cancer
TERT activator-2 (Compound 1030) is a telomerase reverse transcriptase (TERT) activator that can increase the expression of TERT in cells. TERT activator-2 can be used in telomere-related cell lifespan research .

HY-172662

TRF1-TIN2 PPI-IN-1	Telomerase	Cancer
TRF1-TIN2 PPI-IN-1 (Compound 40) is a TRF1-TIN2 interaction inhibitor. TRF1-TIN2 PPI-IN-1 binds to the TRFH domain of TRF1 (K_D = 29 μM) and competitively inhibits the binding of the TIN2 peptide (IC₅₀ = 67 μM). TRF1-TIN2 PPI-IN-1 disrupts the interaction between TRF1 and TIN2 by occupying the hotspot region of the TRF1-TIN2 binding interface. TRF1-TIN2 PPI-IN-1 can expel TRF 1 from the shelterin complex and can be used to study shelterin-related cancers .

HY-122092

FJ-5002	Telomerase	Cancer
FJ-5002 is a telomerase inhibitor with an IC₅₀ of 2 μM. FJ-5002 can induce telomere shortening, increased chromosomal abnormalities, and senescence/crisis-like features in the human leukemia cell line U937. FJ-5002 exhibits antitumor activity and can be used in the study of cancer .

HY-N16070

1-PP-myo-InsP5	Endogenous Metabolite	Others
1-PP-myo-InsP5 is an inositol pyrophosphate. 1-PP-myo-InsP5, as a signaling molecule in mammals, can transmit signals by binding to specific receptors or through non-enzymatic transphosphorylation. 1-PP-myo-InsP5 can be involved in various biological processes such as insulin signaling and telomere length regulation .

HY-D2380

H2S probe 1	G-quadruplex	Cancer
H2S probe 1 (compound 1NND) is a derivative of nitrobenzoxadiazole (NBD) with antitumor activity. H2S probe 1 is cytotoxic to human pancreatic cancer cell MIA PaCa-2 (IC₅₀=77.9 nM) and has a high affinity for human telomeric G-quadruplex (G4) (K_d=1.72 μM). H2S probe 1 can be used in cancer research .

HY-162688

Anticancer agent 239	Telomerase G-quadruplex Apoptosis Ferroptosis	Others
Anticancer agent 239 (Compound 5) is a ligand of hTERT promoter G-quadruplex DNA structures (hTERT G4) (K_d = 1.1 μM), and downregulates hTERT expression. Anticancer agent 239 decreases telomerase activity, shortens telomere length, and induces DNA damage, acute cellular senescence, and apoptosis. Anticancer agent 239 causes mitochondrial dysfunction, disrupts iron metabolism and activates ferroptosis in cancer cells. Anticancer agent 239 inhibits tumor growth in MDA-MB-231 xenograft mouse model .

HY-168890

TRF2-IN-1	Telomerase Apoptosis	Cancer
TRF2-IN-1 (compound F2) is a potent telomere repeat-binding factor 2 (TRF2) inhibitor. TRF2-IN-1 shows antiproliferative activity. TRF2-IN-1 induces apoptosis. TRF2-IN-1 directly bind to the TRF2TRFH domain and selectively inhibits TRF2 protein expression and telomeric localization. TRF2-IN-1 shows anticancer activity. TRF2-IN-1 has the potential for the research of osteosarcoma .

HY-111297

BMVC4	Biochemical Assay Reagents	Cancer
BMVC4 is a G-quadruplex (G4) stabilizer of the human telomeric sequence d[AG3(T2AG3)3]. Screening by circular dichroism (CD) spectroscopy revealed that BMVC4 is more suitable as the core molecule of G4 stabilizers than BMVC. The results showed that BMVC4-12C and BMVC4-8C3O are better candidates for G4 stabilizers and are worthy of further study. A simple and rapid screening method based on Cu2+-induced G4 unfolding can be used to find better G4 stabilizers for potential anticancer applications. CD results showed that the trivalent cations of 9-substituted BMVC derivatives are more suitable as G4 stabilizers than the divalent cations of BMVC. In addition, by monitoring the disappearance of the 291 nm CD band of human telomeres after Cu2+ addition, it was found that the core molecule of G4 stabilizer BMVC4 has better stability.

Cat. No.	Product Name

HY-L034M

Anti-Aging Compound Library Mini	381 compounds
Research has shown that drugs targeting aging pathways demonstrate promising potential in models of age-related diseases such as Alzheimer's disease, cardiovascular diseases, metabolic syndrome, osteoarthritis, and various malignancies. This suggests that intervening in the biological processes of aging may enable synergistic prevention and treatment of multiple chronic diseases. Against the backdrop of the gradual elucidation of core aging mechanisms-including cellular senescence, telomere attrition, epigenetic dysregulation, and chronic inflammation anti-aging research has shifted from traditional phenotypic interventions toward targeting key pathways that regulate biological age. The MCE Anti-Aging Compound Library Mini is precisely built upon this cutting-edge concept. It focuses on aging-related targets validated through genetic or functional studies, comprising 381 compounds designed to provide systematic research tools for aging biology and intervention strategy development. The library covers core mechanisms such as mTOR, SIRT, energy metabolism, clearance of senescent cells, optimization of mitochondrial function, and telomere maintenance. For each target, 1-5 compounds with clear activity and strong representativeness have been carefully selected, spanning the entire translational spectrum from preclinical tool molecules to clinically investigational drugs.

Anti-Aging Compound Library Mini

381 compounds

Research has shown that drugs targeting aging pathways demonstrate promising potential in models of age-related diseases such as Alzheimer's disease, cardiovascular diseases, metabolic syndrome, osteoarthritis, and various malignancies. This suggests that intervening in the biological processes of aging may enable synergistic prevention and treatment of multiple chronic diseases. Against the backdrop of the gradual elucidation of core aging mechanisms-including cellular senescence, telomere attrition, epigenetic dysregulation, and chronic inflammation anti-aging research has shifted from traditional phenotypic interventions toward targeting key pathways that regulate biological age.

The MCE Anti-Aging Compound Library Mini is precisely built upon this cutting-edge concept. It focuses on aging-related targets validated through genetic or functional studies, comprising 381 compounds designed to provide systematic research tools for aging biology and intervention strategy development. The library covers core mechanisms such as mTOR, SIRT, energy metabolism, clearance of senescent cells, optimization of mitochondrial function, and telomere maintenance. For each target, 1-5 compounds with clear activity and strong representativeness have been carefully selected, spanning the entire translational spectrum from preclinical tool molecules to clinically investigational drugs.

HY-L034

Anti-Aging Compound Library	7,297 compounds
Aging is a complex biological process characterized by functional decline of tissues and organs, structural degeneration, and reduced adaptability and resistance, all of which contribute to an increase in morbidity and mortality caused by multiple chronic diseases, such as Alzheimer's disease, cancer, and diabetes. Many theories, which fall into two main categories: programmed and error theories, have been proposed to explain the process of aging, but neither of them appears to be fully satisfactory. The programmed theories imply that aging relies on specific gene regulation, and the error theories emphasize the internal and environmental damages accumulated to living organisms. The damage theories proposed the nine hallmarks that were generally considered to contribute to the aging process: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. MCE Anti-Aging Compound Library contains 7,297 compounds, mainly targeting Sirtuin, mTOR, IGF-1R, AMPK, p53, Telomerase, Mitophagy, Mitochondrial Metabolism, COX, Cytochrome P450, Oxidase, etc. This library is a useful tool for anti-aging research.

Anti-Aging Compound Library

7,297 compounds

Aging is a complex biological process characterized by functional decline of tissues and organs, structural degeneration, and reduced adaptability and resistance, all of which contribute to an increase in morbidity and mortality caused by multiple chronic diseases, such as Alzheimer's disease, cancer, and diabetes. Many theories, which fall into two main categories: programmed and error theories, have been proposed to explain the process of aging, but neither of them appears to be fully satisfactory. The programmed theories imply that aging relies on specific gene regulation, and the error theories emphasize the internal and environmental damages accumulated to living organisms. The damage theories proposed the nine hallmarks that were generally considered to contribute to the aging process: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication.

MCE Anti-Aging Compound Library contains 7,297 compounds, mainly targeting Sirtuin, mTOR, IGF-1R, AMPK, p53, Telomerase, Mitophagy, Mitochondrial Metabolism, COX, Cytochrome P450, Oxidase, etc. This library is a useful tool for anti-aging research.

Cat. No.	Product Name	Type

HY-15943

6-TAMRA 1 Publications Verification 6-Carboxytetramethylrhodamine	Fluorescent Dyes
6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays .

HY-D1668

Biotin-11-dCTP	Fluorescent Dyes
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

Biotin-11-dCTP

Fluorescent Dyes

Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

HY-D2380

H2S probe 1	Fluorescent Dyes
H2S probe 1 (compound 1NND) is a derivative of nitrobenzoxadiazole (NBD) with antitumor activity. H2S probe 1 is cytotoxic to human pancreatic cancer cell MIA PaCa-2 (IC₅₀=77.9 nM) and has a high affinity for human telomeric G-quadruplex (G4) (K_d=1.72 μM). H2S probe 1 can be used in cancer research .

Cat. No.	Product Name	Type

HY-W543137

PT-ttpy	Biochemical Assay Reagents
Pt-ttpy, a metallo-organic complex and potent G-quadruplex ligand, effectively triggers substantial telomere-related DNA damage in cancer cells by inhibiting telomerase and/or telomere functions, while also causing various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

Cat. No.	Product Name	Target	Research Area

HY-P11224

RMI-L4	DNA/RNA Synthesis	Cancer
RMI-L4 is an efficient cyclic peptide inhibitor that can specifically disrupt the interaction between FANCM and RMI proteins with an IC₅₀ of 54 nM. RMI-L4 engages the FANCM-binding pocket of RMI1/2 with nanomolar affinity (K_D = 2.5 nM). RMI-L4 cannot penetrate the cell membrane and can be used to study the FANCM-RMI pathway targeting cancer with alternate lengthening of telomeres (ALT) .

HY-P5270

Hexapeptide-12	Peptides	Metabolic Disease
Hexapeptide-12isa bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .

HY-P5279

Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine	Peptides	Metabolic Disease
Palmitoyl dipeptide-7 is a bioactive peptide with anti-aging effects that has been reported for use as a cosmetic ingredient.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1485

Cycloastragenol 5+ Cited Publications Astramembrangenin; Cyclosieversigenin	Triterpenes other families Terpenoids Plants Source Classification	Telomerase
Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .

HY-N1485R

Cycloastragenol (Standard) Astramembrangenin (Standard); Cyclosieversigenin (Standard)	Triterpenes Structural Classification other families Terpenoids Plants Source Classification	Reference Standards Telomerase
Cycloastragenol (Standard) is the analytical standard of Cycloastragenol. This product is intended for research and analytical applications. Cycloastragenol (Astramembrangenin), the active form of astragaloside IV, has anti-oxidant, anti-inflammatory, anti-aging, anti-apoptotic, and cardiovascular protective effects. Cycloastragenol is a potent telomerase activator and can lengthen telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties .

HY-N16070

1-PP-myo-InsP5	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
1-PP-myo-InsP5 is an inositol pyrophosphate. 1-PP-myo-InsP5, as a signaling molecule in mammals, can transmit signals by binding to specific receptors or through non-enzymatic transphosphorylation. 1-PP-myo-InsP5 can be involved in various biological processes such as insulin signaling and telomere length regulation .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704039

	TERT Protein, Human (His) CMM9; DKCA2; DKCB4; EST2; HEST2; htert; hTRT; PFBMFT1; TCS1; Telomerase associated protein 2; Telomerase catalytic subunit; Telomerase reverse transcriptase; Telomerase-associated protein 2; Telomere Reverse Transcriptase; TERT; TERT_HUMAN; TP2; TRT	Human	E. coli
	TERT Protein, Human (His) is the recombinant human-derived TERT protein, expressed by E. coli, with N-6*His tag.

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Host:	Mouse (1) Rabbit (4)
Reactivity:	Human (5) Rat (1) Mouse (1)
Application:	IHC-P (1) ICC/IF (2) IF-Tissue (1) IP (1) IHC-F (1) WB (5) FC (1) ELISA (1)
Isotype:	IgG (4) IgG1 (1)
Conjugation:	Non-conjugated (4)
Clonality:	Polyclonal (1) Monoclonal (3) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P810331

	POT1 Antibody (YA9653) Protection of Telomeres protein 1, POT1, POT1-like Telomere end-binding protein, hPot1	WB, ICC/IF, IF-Tissue, IP	Human
	POT1 Antibody (YA9653) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to POT1.

HY-P81945

	POT1 Antibody (YA1690) POT1; Protection of Telomeres protein 1; hPot1; POT1-like Telomere end-binding protein	WB	Human
	POT1 Antibody (YA1690) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POT1.

HY-P81945A

	POT1 Antibody (YA1690)(PBS only) POT1; Protection of Telomeres protein 1; hPot1; POT1-like Telomere end-binding protein	WB	Human
	POT1 Antibody (YA1690) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to POT1.

HY-P81110

	TERT Antibody Telomerase catalytic subunit; EST2; hEST2; TCS1; Telomerase associated protein 2; Telomere Reverse Transcriptase; TP2; TRT; Telomerase reverse transcriptase; Telomerase Catalytic Subunit; Telomerase-associated protein 2; TERT_HUMAN.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	TERT Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to TERT.

HY-P81110A

	TERT Antibody (YA3439) Telomerase catalytic subunit; EST2; hEST2; TCS1; Telomerase associated protein 2; Telomere Reverse Transcriptase; TP2; TRT; Telomerase reverse transcriptase; Telomerase Catalytic Subunit; Telomerase-associated protein 2; TERT_HUMAN.	WB	Human
	TERT Antibody (YA3439) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TERT.

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HY-D1668

Biotin-11-dCTP		Labeling and Fluorescence Imaging
Biotin-11-dCTP is a biotinylated deoxynucleoside triphosphate and an important DNA labeling reagent. In random primer DNA labeling reactions, Biotin-11-dCTP incorporates into newly synthesized DNA strands to generate labeled DNA probes suitable for hybridization applications. In addition, Biotin-11-dCTP can serve as a substrate for terminal deoxynucleotidyl transferase to end-label oligonucleotides for telomere sequence detection, or to label the cut ends of linearized DNA molecules, thereby supporting streptavidin-based electron microscopy analysis. For example, Biotin-11-dCTP can label the cut ends of linearized DNA molecules under the action of dGTP and avian myeloblastosis virus reverse transcriptase .

Cat. No.	Product Name		Classification

HY-18762

6-Thio-2'-Deoxyguanosine 2 Publications Verification 6-thio-dG; β-TGdR		Nucleoside Analogs Guanosine
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.

HY-12854

Imetelstat GRN163L		Antisense Oligonucleotides
Imetelstat (GRN163L) is a 13-mer oligonucleotide and competitive Telomerase inhibitor. Imetelstat binds with high affinity to the template region of the RNA component of human telomerase. Imetelstat induces Apoptosis. Imetelstat is capable of selectively eliminating myelofibrosis hematopoietic stem cells. Imetelstat leads to the loss of a cancer cell's ability to maintain telomere length, resulting in the inhibition of cell proliferation .

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Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Telomere

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Natural
Products