188630-47-9
Chemical Structure
SYUIQ-5
- CAS No.: 188630-47-9
- Formula:C20H22N4
- Molecular Weight:318.42
IUPAC Name: N1-(10H-indolo[3,2-b]quinolin-11-yl)-N3,N3-dimethylpropane-1,3-diamine
InChIKey: CTDCVGDSVHUYMA-UHFFFAOYSA-N
SMILES: CN(C)CCCNC(C1=C(C=CC=C1)N=C23)=C3NC4=C2C=CC=C4
Biological Activity: SYUIQ-5 is a G-quadruplex ligand. SYUIQ-5 stabilizes G-quadruplex and induce senescence. SYUIQ-5 inhibits c-myc gene promoter activity. SYUIQ-5 induces cancer cells autophagy by triggering telomere damage through TRF2 delocalization from telomeres[1].
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SYUIQ-5 | 99.03% | SYUIQ-5 is a G-quadruplex ligand. SYUIQ-5 stabilizes G-quadruplex and induce senescence. SYUIQ-5 inhibits c-myc gene promoter activity. SYUIQ-5 induces cancer cells autophagy by triggering telomere damage through TRF2 delocalization from telomeres. | ||||||||||||||||||||
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Keywords