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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
Thiadiazole
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "Thiadiazole" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: HOE 140 acetate
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CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM .
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Halicin (SU3327) is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM. Halicin also inhibits protein-protein interactions between JNK and JNK Interacting Protein (JIP) with an IC50 of 239 nM. Halicin shows less active against p38α and Akt kinase .
Cat. No.: HY-W032388
CAS No.: 1072-71-5
Cat. No.: HY-W074975
CAS No.: 14949-00-9
Synonyms: 5-Amino-1,3,4-Thiadiazole-2-sulfonamide
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CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is a selective inhibitor of carbonic anhydrase B (HCA-B) and isoforms I, II, IV, and VII. CL 5343 has a Ki of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer .
Cat. No.: HY-W006187
CAS No.: 13227-01-5
Synonyms: (Rac)-H-Phg(4-Me)-OH
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Cat. No.: HY-W012675
CAS No.: 2349-67-9
Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
Cat. No.: HY-119403
CAS No.: 25445-77-6
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4-Phenyl-1,2,3-thiadiazole is an CYP2B4 and CYP2E1 inhibitor. 4-Phenyl-1,2,3-thiadiazole inhibits the oxidation of 1-phenylethanol to acetophenone by CYP2B4 and CYP2E1 .
Cat. No.: HY-W074975R
CAS No.: 14949-00-9
Synonyms: 5-Amino-1,3,4-Thiadiazole-2-sulfonamide (Standard)
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CL 5343 (Standard) is the analytical standard of CL 5343. This product is intended for research and analytical applications. CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is an inhibitor of human carbonic anhydrase B (HCA-B). CL 5343 can serve as a CA9 ligand to achieve the targeted delivery of maytansinoid to the cell membrane of SKRC52 renal cancer cells .
Cat. No.: HY-114955
CAS No.: 152467-47-5
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MTTC is a 1,2,3-thiadiazole compound that exhibits mechanism-based inactivation, resulting in the inactivation of cytochrome P450 2E1 activity .
Cat. No.: HY-106817
CAS No.: 111393-84-1
Synonyms: LY 217896
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Amitivir (LY 217896), a thiadiazole derivative, possesses broad antiviral activity against orthomyxo- and paramyxoviruses. Amitivir is effective against influenza A and B viruses .
Cat. No.: HY-155240
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Tyrosinase-IN-13 (compound 3c), a derivative of Flurbiprofen (HY-10582), is a potent, non-competitive tyrosinase inhibitor (IC50=68 μM; Ki=36.3 μM). Tyrosinase-IN-13 is cytotoxic against hepatocellular carcinoma (HepG2), colorectal cancer (HT-29), and melanoma (B16F10) .
Cat. No.: HY-179057
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GSTA4-IN-1 (Compound 3a) is a potent and competitive inhibitor of glutathione S-transferase A4 (GSTA4), with an IC50 of 3.12 μM and a Ki of 2.38 μM. GSTA4-IN-1 is cytotoxic to colorectal cancer cells. GSTA4-IN-1 can be used for research on colorectal cancer .
Cat. No.: HY-119480R
CAS No.: 19622-55-0
Megazol (Standard) is the analytical standard of Megazol. This product is intended for research and analytical applications. Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
Cat. No.: HY-W075198
CAS No.: 15311-09-8
Synonyms: 2,5-Bis(4-pyridyl)-1,3,4-Thiadiazole
2,5-Di(pyridin-4-yl)-1,3,4-thiadiazole (2,5-Bis(4-pyridyl)-1,3,4-thiadiazole) is a metal-organic framework (MOF).
Cat. No.: HY-W075196
CAS No.: 15362-52-4
Synonyms: 2,5-Di(3-pyridyl)-1,3,4-Thiadiazole
2,5-Di(pyridin-3-yl)-1,3,4-thiadiazole (2,5-Di(3-pyridyl)-1,3,4-thiadiazole) is a metal-organic framework (MOF).
Cat. No.: HY-W012690R
CAS No.: 29490-19-5
Synonyms: 5-Methyl-1,3,4-Thiadiazole-2-thiol (Standard)
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5-Methyl-1,3,4-thiadiazole-2(3H)-thione (Standard) is the analytical standard of 5-Methyl-1,3,4-thiadiazole-2(3H)-thione. This product is intended for research and analytical applications.
Cat. No.: HY-W013947
CAS No.: 5393-99-7
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4,5-Diphenyl-1,2,3-thiadiazole is a platelet aggregation inhibitor with an IC50 of 3.2 μg/mL against collagen-induced platelet aggregation. 4,5-Diphenyl-1,2,3-thiadiazole can be used in thrombosis-related studies.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
