4,5-Diphenyl-1,2,3-thiadiazole
4,5-Diphenyl-1,2,3-thiadiazole is a platelet aggregation inhibitor with an IC50 of 3.2 μg/mL against collagen-induced platelet aggregation. 4,5-Diphenyl-1,2,3-thiadiazole can be used in thrombosis-related studies.
For research use only. We do not sell to patients.
- CAS No.: 5393-99-7
- Formula: C14H10N2S
- Molecular Weight:238.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
4,5-Diphenyl-1,2,3-thiadiazole (Compound 5v) inhibits collagen-induced platelet aggregation in platelet-rich plasma, with an IC50 of 3.2 μg/mL and a relative potency of 0.03 compared with Flurbiprofen (HY-10582).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 5393-99-7
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Molecular Weight 238.31
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Formula C14H10N2S
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SMILES
C1(C2=CC=CC=C2)=C(C3=CC=CC=C3)SN=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)