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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
VH032-C2-PEG4-N3
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "VH032-C2-PEG4-N3" in MCE Product Catalog:
Cat. No.: HY-130654
CAS No.: 2597167-24-1
Synonyms: VH032-C2-PEG4-N3
Research Areas:
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. (S,R,S)-AHPC-C2-PEG4-N3 can be used in the synthesis of vRucaparib-TP4 (HY-130647). vRucaparib-TP4 a highly potent PARP1 degrader with a half-maximal degrading concentration (DC50) of 82 nM . (S,R,S)-AHPC-C2-PEG4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-P11026
Synonyms: DOTA-PEG4-TMVP1446
Cat. No.: HY-P10590
CAS No.: 1801418-23-4
Target:
Research Areas:
Cat. No.: HY-P10872
Cat. No.: HY-P10906
CAS No.: 2868285-05-4
Target:
Research Areas:
Cat. No.: HY-P11455
Cat. No.: HY-P11773
CAS No.: 1094848-94-8
Research Areas:
Cat. No.: HY-P11774
CAS No.: 1094848-99-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
