1 Result for "

VU-6052254

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "VU-6052254" in MCE Product Catalog:

Cat. No.: HY-180143
CAS No.: 3035701-02-8
Target:  

mAChR Drug Derivative

Research Areas:  

Neurological Disease

VU6052254, a derivative of VU0467319 (HY-173396), is a selective, potent, orally active and brain-penetrant muscarinic M1 acetylcholine receptor (mAChR1) positive allosteric modulator with an EC50 of 59 nM. VU6052254 has no activity on the M2-5 receptor (EC50 > 30 μM). VU6052254 can improve memory recognition ability and reverse the cognitive impairment induced by Scopolamine (HY-N0296) with minimum effective dose both of 1 mg/kg. VU6052254 can be used for the research of neurological disease, such as Alzheimer's disease .
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