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Vitexin 4'-glucoside

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Caspase (1) Interleukin Related (1) JNK (1) Lactate Dehydrogenase (1) p38 MAPK (1) TNF Receptor (1)
By Research Areas:	Cardiovascular Disease (1) Metabolic Disease (2)

Inhibitors & Agonists

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

**Vitexin 4'-glucoside** 4'-O-GlucosylVitexin	Others	Metabolic Disease
Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta .

**Vitexin-4''-O-glucoside** 4''-O-GlucosylVitexin	JNK p38 MAPK Interleukin Related TNF Receptor Caspase Lactate Dehydrogenase Apoptosis	Cardiovascular Disease Metabolic Disease
Vitexin-4''-O-glucoside (4''-O-Glucosylvitexin) is an orally active natural flavonoid component with multiple pharmacological effects including antioxidation, anti-inflammation, cytoprotection and anti-apoptosis. Vitexin-4''-O-glucoside regulates the MAPK signaling pathway by downregulating the phosphorylation levels of JNK and p38, thereby blocking endoplasmic reticulum stress responses. Vitexin-4''-O-glucoside alleviates oxidative stress by reducing MDA content and upregulating the activities of SOD and CAT, attenuates inflammation by downregulating the expressions of inflammatory factors TNF-α, IL-1β and IL-6, and also reduces LDH release and inhibits caspase-3 activation. Vitexin-4''-O-glucoside effectively improves drug-induced acute liver injury and exerts significant protective effects against myocardial hypoxia/reoxygenation injury. Vitexin-4''-O-glucoside can be used in studies on acute liver injury, cardiovascular diseases and myocardial hypoxia-reoxygenation injury .

**Vitexin 4'-glucoside** 4'-O-GlucosylVitexin	Flavonoids other families Classification of Application Fields Flavones Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Others
Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta .

**Vitexin-4''-O-glucoside** 4''-O-GlucosylVitexin	Cardiovascular Disease Structural Classification Flavonoids Classification of Application Fields Flavones Rosaceae Phenols Polyphenols Crataegus pinnatifida Bge. Plants Disease Research Fields Source Classification	JNK p38 MAPK Interleukin Related TNF Receptor Caspase Lactate Dehydrogenase Apoptosis
Vitexin-4''-O-glucoside (4''-O-Glucosylvitexin) is an orally active natural flavonoid component with multiple pharmacological effects including antioxidation, anti-inflammation, cytoprotection and anti-apoptosis. Vitexin-4''-O-glucoside regulates the MAPK signaling pathway by downregulating the phosphorylation levels of JNK and p38, thereby blocking endoplasmic reticulum stress responses. Vitexin-4''-O-glucoside alleviates oxidative stress by reducing MDA content and upregulating the activities of SOD and CAT, attenuates inflammation by downregulating the expressions of inflammatory factors TNF-α, IL-1β and IL-6, and also reduces LDH release and inhibits caspase-3 activation. Vitexin-4''-O-glucoside effectively improves drug-induced acute liver injury and exerts significant protective effects against myocardial hypoxia/reoxygenation injury. Vitexin-4''-O-glucoside can be used in studies on acute liver injury, cardiovascular diseases and myocardial hypoxia-reoxygenation injury .

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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