1 Result for "

W(Dab)L

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "W(Dab)L" in MCE Product Catalog:

W(Dab)L
W(Dab)L
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Cat. No.: HY-P11821
Target:  

Bacterial

Research Areas:  

Infection

W(Dab)L is a cationic membrane-disrupting antimicrobial peptide with protease stability, salt tolerance, and no induction of drug resistance. W(Dab)L is effective against planktonic MRSA, MRSA biofilms, and Pseudomonas aeruginosa, and exhibits low cytotoxicity to mammalian cells. As a bactericide, W(Dab)L selectively interacts with negatively charged bacterial membranes, triggering membrane permeabilization, deformation, disintegration, intracellular substance leakage, and ultimately leading to cell lysis. W(Dab)L maintains its chemical integrity and antimicrobial activity upon exposure to proteases and human serum. W(Dab)L can be used in studies of methicillin-resistant Staphylococcus aureus infections .
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