1 Result for "

Y 590

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Y 590" in MCE Product Catalog:

Cat. No.: HY-123366
CAS No.: 70386-06-0
Research Areas:  

Cardiovascular Disease

Y-590 is an orally active platelet cyclic adenosine monophosphate phosphodiesterase (cAMP-PDE) inhibitor with an IC50 of 0.9 nM against rabbit cAMP-PDE. Y-590 inhibits platelet aggregation, disaggregates aggregated platelets, suppresses collagen-induced platelet release, reduces platelet retention and inhibits cAMP degradation in platelets. Y-590 enhances PGI2-mediated elevation of intracellular cAMP in platelets and exerts a synergistic effect with PGI2 on ADP-induced platelet aggregation. Y-590 can be used in studies related to thrombotic diseases and thrombosis .
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