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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
acetyllysine
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "acetyllysine" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-19541
CAS No.: 1640282-31-0
Research Areas:
I-CBP112, a chemical probe, is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor, that inhibits the CBP/p300 bromodomains, enhances acetylation by p300.
5
5 Cited Publications
Cat. No.: HY-P71596
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIRT1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog) 1; Sirtuin 1; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); SIR2L1; Protein acetyllysine N-Acetyltransferase; NAD-Dependent Protein Dea
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P2161B
Target:
Research Areas:
3
3 Cited Publications
Target:
Research Areas:
GSK2801, a chemical probe, is a potent, selective, orally active and cell active acetyl-lysine competitive BAZ2A and BAZ2B bromodomains inhibitor with Kd values of 136 nM and 257 nM, respectively. GSK2801 shows >50-fold selectivity for BAZ2A/B over BRD4 .
Target:
Research Areas:
AZ13824374 is a potent and selective ATAD2 bromodomain inhibitor (pIC50 of 6.9 in HCT116 cells). AZ13824374 disrupts chromatin interactions and gene transcription by binding to the acetyl-lysine binding site of the ATAD2 bromodomain. AZ13824374 has anticancer activity against breast cancer .
Target:
Research Areas:
GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments .
Cat. No.: HY-P5544
CAS No.: 60230-21-9
Synonyms: N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid
Target:
Research Areas:
Cat. No.: HY-P2161
CAS No.: 872719-49-8
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Cat. No.: HY-P2115
CAS No.: 127932-90-5
Target:
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Cat. No.: HY-P5544A
Synonyms: N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid TFA
Target:
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Cat. No.: HY-P2161A
Target:
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Cat. No.: HY-P86733A
Synonyms: Acetylated Lysine; acetyllysine; Ac-lysine; Ac lysine; Ac-K; Ac K; Ac-Lys; Ac Lys; acetyl-Lysine; acetyl Lys; Ac-Lysine;
Cat. No.: HY-107477R
CAS No.: 1693766-04-9
Research Areas:
GSK8573 (Standard) is the analytical standard of GSK8573 (HY-107477). This product is intended for research and analytical applications. GSK8573 is an inactive control compound for GSK2801 (acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains). GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy. GSK8573 can be used as a structurally related negative control compound in biological experiments .
Cat. No.: HY-183922
CAS No.: 2735720-80-4
Target:
Research Areas:
SRX3212 is a potent PI3Kα/BRD4 inhibitor with human IC50 values of 22 nM, 3.7 nM, and 32 nM for PI3Kα, BRD4BD1, and BRD4BD2, respectively. SRX3212 inhibits PI3K kinase activity and blocks acetyllysine binding function of BRD4BD1 and BRD4BD2. SRX3212 can be used for the research of mantle cell lymphoma, colon carcinoma, neuroblastoma, prostate cancer[1].
Cat. No.: HY-115541
CAS No.: 1877286-69-5
Research Areas:
BRD4-IN-41 is a BRD4 inhibitor with an IC50 of 34 nM. BRD4-IN-41 also inhibits JAK2, FLT3, RET, ROS1, NTRK3, PDGFRb, and FGFR1 kinases with IC50 values ranging from 0.9 nM to 43 nM. BRD4-IN-41 inhibits acetyl-lysine binding site of BRD4, downregulates c-MYC, reduces phosphorylated STAT3 levels, induces G1 cell cycle arrest and apoptosis, thereby inhibiting cancer cells growth. BRD4-IN-41 can be used for the research of cancer, such as multiple myeloma and acute myeloid leukemia .
Cat. No.: HY-P701613
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CECR2; Cat Eye Syndrome Chromosome Region, Candidate 2; CECR2 Histone Acetyl-Lysine Reader; Cat Eye Syndrome Critical Region Protein 2; Chromatin Remodeling Regulator CECR2; Alternative Protein CECR2; KIAA1740
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
