2 Results for "

ampullary carcinoma

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ampullary carcinoma" in MCE Product Catalog:

Cat. No.: HY-175589
Research Areas:  

Cancer

XSJ81 is an orally active anti-cancer agent. XSJ81 significantly inhibits the proliferation of ampullary carcinoma (AC) DPC-X3 cells with an IC50 of 0.655 μM. XSJ81 inhibits the colony formation, arrests cell cycle at the G2/M phase and inhibits the migration in DPC-X3 cells. XSJ81 induces DNA damage and apoptosis in DPC-X3 cells. XSJ81 demonstrates significant anti-tumor efficacy in mice bearing DPC-X3 xenografts. XSJ81 can be used for the study of ampullary carcinoma .
loading...
    loading...
Cat. No.: HY-174151
CAS No.: 203923-65-3
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

XSJ110 is a potent irreversible topoisomerase I (Topo I) inhibitor with an IC50 value of 0.133 μM. XSJ110 blocks DNA topoisomerization, induces DNA double-strand breaks, and triggers cell cycle arrest at G0/G1 phase, inducing tumor cell apoptosis. XSJ110 is promising for research of ampullary carcinoma (AC) .
loading...
    loading...