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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
anthrax toxin
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "anthrax toxin" in MCE Product Catalog:
7
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Cat. No.: HY-P9932
CAS No.: 1351337-07-9
Synonyms: ETI 204
Target:
Research Areas:
Cat. No.: HY-P9957
CAS No.: 565451-13-0
Synonyms: ABthrax
Cat. No.: HY-W157376
CAS No.: 155773-72-1
Target:
PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems .
Synonyms: 7-Desacetoxy-6,7-dehydrogedunin
Target:
PERK Prokineticin Receptor P2X Receptor Caspase NOD-like Receptor (NLR) Pyroptosis Tyrosinase
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
7DG (7-Desacetoxy-6,7-dehydrogedunin) is a PKR inhibitor, P2X7 purinergic receptor inhibitor, and skin-lightening agent. 7DG binds outside the ATP-catalytic domain of PKR, blocks the kinase activity-independent protein-protein interactions of PKR, inhibits the phosphorylation and activity of PKR, disrupts ASC assembly and caspase-1 activation, and suppresses the activation of the NLRP1 inflammasome. 7DG inhibits pyroptosis, suppresses the ATP-P2X7 signaling pathway, and abolishes ATP-induced increases in the expression levels of MITF, tyrosinase, PMEL/gp100, and melanin content. 7DG exerts skin-lightening effects in cultured skin in vitro. 7DG can be used in research related to chronic obstructive pulmonary disease, gout, type 2 diabetes, Alzheimer's disease, and hyperpigmentary skin disorders .
Cat. No.: HY-178898
CAS No.: 13072-74-7
Cat. No.: HY-P76153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax toxin Receptor; CMG2; ANTXR2 Protein; anthrax toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Cat. No.: HY-P76151
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax toxin Receptor; CMG2; ANTXR2 Protein; anthrax toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Cat. No.: HY-P76152
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax toxin Receptor; CMG2; ANTXR2 Protein; anthrax toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Cat. No.: HY-P700656
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax toxin Receptor; CMG2; ANTXR2 Protein; anthrax toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Cat. No.: HY-P7521A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR1; FLJ10601; ANTXR Cell Adhesion Molecule 1; Tumor Endothelial Marker 8 Precursor; anthrax toxin Receptor 1; anthrax toxin Receptor; TEM8; ANTXR1 Protein; ATR; 2310008J16Rik; Tumor Endothelial Marker 8; 2810405N18Rik; FLJ21776; GAPO
Cat. No.: HY-P77226
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR1; FLJ10601; ANTXR Cell Adhesion Molecule 1; Tumor Endothelial Marker 8 Precursor; anthrax toxin Receptor 1; anthrax toxin Receptor; TEM8; ANTXR1 Protein; ATR; 2310008J16Rik; Tumor Endothelial Marker 8; 2810405N18Rik; FLJ21776; GAPO
Cat. No.: HY-P705240
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR1; FLJ10601; ANTXR Cell Adhesion Molecule 1; Tumor Endothelial Marker 8 Precursor; anthrax toxin Receptor 1; anthrax toxin Receptor; TEM8; ANTXR1 Protein; ATR; 2310008J16Rik; Tumor Endothelial Marker 8; 2810405N18Rik; FLJ21776; GAPO
Cat. No.: HY-183851
CAS No.: 639048-45-6
KKL-55 is a broad-spectrum antibacterial agent that inhibits the trans-translation pathway and the ClpXP protease. KKL-55 suppresses trans-translation of non-stop mRNA, interferes with the binding of EF-Tu to tmRNA, and inhibits the proteolysis of substrates by ClpXP. KKL-55 blocks spore germination of Bacillus anthracis and protects macrophages from damage induced by anthrax toxin. By virtue of its inhibitory effect on ClpXP, KKL-55 synergistically enhances the antibacterial activity of antibiotics against drug-resistant Staphylococcus aureus. KKL-55 can be used in studies related to bacterial infections .
Cat. No.: HY-179376
Anti-virulence factor-IN-3 (Compound 21) is a covalent β-aminosulfinyl type anthrax edema factor (EF) inhibitor, with a Ki value of 0.44 μM. Anti-virulence factor-IN-3 generates an active ethylene sulfinyl intermediate, which forms an irreversible covalent bond with the Lys residue at the active center of EF, permanently inhibiting the adenylate cyclase activity of EF. Anti-virulence factor-IN-3 effectively inhibits the cAMP production induced by EF, with an EC50 value of 0.15 μM. Anti-virulence factor-IN-3 can be used for research on anthrax Infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
