CMG-2/ANTXR2 Protein, Mouse (HEK293, His)

CMG-2/ANTXR2 is essential for cell adhesion and communication with laminin and the extracellular matrix. It exhibits specific binding to laminin, emphasizing its role in laminin-dependent cellular processes. CMG-2/ANTXR2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CMG-2/ANTXR2 protein, expressed by HEK293 , with C-His labeled tag.

CMG-2/ANTXR2 protein is indispensable for cellular interactions with laminin and the extracellular matrix, indicating its pivotal role in mediating adhesion and communication between cells and their surrounding environment. This protein exhibits a specific binding affinity for laminin, emphasizing its involvement in the regulation of laminin-dependent cellular processes. Furthermore, there is a suggestion of potential interaction with collagen type IV, broadening its scope of engagement with key components of the extracellular matrix. The capacity of CMG-2/ANTXR2 to bind to laminin and possibly collagen type IV underscores its significance in cellular adhesion and matrix-related functions, contributing to the intricate framework of cellular interactions within tissues.

Measured by its binding ability in a functional ELISA. Immobilized anthrax protective antigen (PA) at 1.5 µg/mL can bind Mouse CMG-2. The ED₅₀ for this effect is 1.329 μg/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized anthrax protective antigen (PA) at 1.5 µg/mL can bind Mouse CMG-2. The ED₅₀ for this effect is 1.329 μg/mL.

Mouse

HEK293

C-His

Q6DFX2 (Q32-G318)

71914  [NCBI]

Extracellular Domain

QAQEQPSCKKAFDLYFVLDKSGSVANNWIEIYNFVHQLTERFVSPEMRLSFIVFSSQATIILPLTGDRYKIGKGLEDLKAVKPVGETYIHEGLKLANEQIQNAGGLKASSIIIALTDGKLDGLVPSYAENEAKKSRSLGASVYCVGVLDFEQAQLERIADSKDQVFPVKGGFQALKGIINSILAQSCTEILELSPSSVCVGEKFQVVLTGRAVTSISHDGSVLCTFTANSTYTKSEKPVSIQPSSILCPAPVLNKDGETLEVSISYNDGKSAVSRSLTITATECTNG

Approximately 32 kDa.

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  ≥ 95%, as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.