4 Results for "

anti- human VISTA

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "anti- human VISTA" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99040
CAS No.: 1969313-51-6
Synonyms: JNJ-61610588; CI-8993; VSTB112

Target:  

VISTA

Research Areas:  

Cancer

Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .
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1
1 Cited Publications
Cat. No.: HY-P991447

Target:  

VISTA

Research Areas:  

Cancer

Anti-VSIR/VISTA Antibody (SG7) is an antibody targeting VISTA, with a Kd of 0.14 nM for human VISTA and 1 nM for mouse VISTA. Anti-VSIR/VISTA Antibody (SG7) blocks the function of VISTA, prevents VISTA from binding to T cells, restores suppressed T cell activation, and blocks the interactions between VISTA and PSGL-1 as well as VSIG3. Anti-VSIR/VISTA Antibody (SG7) slows tumor growth, reduces PMN-MDSCs, and increases the numbers of CD4 + and CD8 + T cells in the tumor microenvironment. Anti-VSIR/VISTA Antibody (SG7) can be used in studies related to melanoma, colon cancer, and breast cancer .
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Cat. No.: HY-147179
CAS No.: 2734878-18-1
Purity:  99.47%
Target:  

ADC Payloads

Research Areas:  

Inflammation/Immunology

INX-SM-56 is a cytotoxin that can be used for the synthesis of anti-VISTA antibody agent conjugate. VISTA: V-region Immunoglobulin-containing Suppressor of T cell Activation .
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Cat. No.: HY-P991765

Target:  

VISTA

Research Areas:  

Inflammation/Immunology Cancer

Anti-VISTA Antibody (GG8) reacts with human VISTA. Endogenous VISTA has inhibitory effects both as a ligand on APCs and as a receptor on T cells. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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