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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
anti-silencing function 1A histone chaperone
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "anti-silencing function 1A histone chaperone" in MCE Product Catalog:
Cat. No.: HY-P70119
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ASF1A; HAsf1A; anti-silencing function 1A histone chaperone; HAsf1; CIA; HCIA; anti-silencing function Protein 1 Homolog A; ASF1 anti-silencing function 1 Homolog A (S. Cerevisiae); CCG1-Interacting Factor A; ASF1 anti-silencing function 1 Homolog A; Hist
Species:
Human
Source:
E. coli
Cat. No.: HY-182037
Target:
Research Areas:
Multi-target kinase-IN-9 is a multi-target enzyme inhibitor with antiproliferative and antiangiogenic activities, and exhibits remarkable selectivity against hepatocellular carcinoma cells. By broadly binding to the active sites or ATP-binding regions of multiple key enzymes including DNA polymerase β, Pyruvate Kinase M2 (PKM2), Multi-target kinase-IN-9 comprehensively disrupts DNA repair and replication, glycolysis, chromatin dynamics and transcriptional programs, and blocks the self-renewal of cancer stem cells. Multi-target kinase-IN-9 induces genomic instability, lysosomal dysfunction and autophagic flux impairment, thereby triggering tumor cell death, effectively inhibiting tumor proliferation, invasion, metastasis and angiogenesis, and significantly reducing tumor volume in xenograft models. Multi-target kinase-IN-9 is applicable to hepatocellular carcinoma-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
