27 Results for "

apoE4

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "apoE4" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-N0762
CAS No.: 31524-62-6
Isobavachin is an orally active, blood-brain barrier-penetrating prenylated flavonoid present in Psoralea corylifolia. Isobavachin inhibits human CYP2B6, CYP2C9, CYP2C19, UGT1A1, UGT1A9, and UGT2B7. Isobavachin suppresses MAPK activation, NF-κB nuclear translocation, overexpression of iNOS/COX-2, FcεRI-mediated signaling pathways, and RANKL-induced osteoclastogenesis. Isobavachin induces autophagy, cytotoxicity, neuronal differentiation, and NRF2 activation; it alleviates oxidative damage, inflammatory responses, apoptosis, iron accumulation, mitochondrial biogenesis, and mast cell degranulation. Isobavachin is applicable to research related to liver injury, inflammatory diseases, osteoporosis, liver cancer, prostate cancer, glioma, periodontitis-induced bone loss, and Alzheimer's disease [4] .
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2
2 Cited Publications
Cat. No.: HY-P7531
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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1
1 Cited Publications
Cat. No.: HY-103076
CAS No.: 1016456-76-0
Purity:  97.21%
Target:  

Apolipoprotein

Research Areas:  

Neurological Disease

EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas .
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1
1 Cited Publications
Cat. No.: HY-P701096
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Rat
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1 Cited Publications
Cat. No.: HY-P7532
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-176434
CAS No.: 2767324-34-3
Target:  

Sirtuin

Research Areas:  

Neurological Disease

DDL-218 is an orally active and potent SirT1 inhibitor. DDL-218 enhances SirT1 in ApoE4-expressing neurons and a murine AD model. DDL-218 can be used in the study of Alzheimer's disease .
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Cat. No.: HY-RS00849
Research Areas:  

Others

APOE Human Pre-designed siRNA Set A contains three designed siRNAs for APOE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-187270S
[U- 15N]-ApoE4 is the 15N-labeled ApoE4. Apolipoprotein E4 (ApoE4) is a significant genetic risk factor for Alzheimer's disease and is closely linked to cardiovascular diseases-such as atherosclerosis-through its influence on lipid metabolism. This isotope can be used in NMR studies of disease mechanisms and in mass spectrometry analysis.
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Cat. No.: HY-103076R
CAS No.: 1016456-76-0
Research Areas:  

Neurological Disease

EZ-482 (Standard) is the analytical standard of EZ-482 (HY-103076). This product is intended for research and analytical applications. EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas .
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Cat. No.: HY-P11677
Research Areas:  

Neurological Disease

CPO_Aβ17-21P is a apoE/Aβ interaction inhibitor with an IC50 of 1.02 nM. CPO_Aβ17-21P significantly inhibits ApoE4-mediated aggregation of Aβ40 and Aβ42. CPO_Aβ17-21P significantly improves cognitive function and comprehensively alleviates Alzheimer's disease (AD)-related pathologies in mouse models. CPO_Aβ17-21P is applicable to the research of AD .
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Cat. No.: HY-P700853
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P78542A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P78542
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P78239
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P72083
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P704412
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P72084
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P78062
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P701051
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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Cat. No.: HY-P704410
Purity:  ≥ 90%, as determined by SDS-PAGE.
Synonyms: apoE; Apolipoprotein E3; Prev. AD2; APO-E; Alzheimer Disease 2 (apoE*E4-Associated, Late Onset); apoE4; Apolipoprotein E Isoform 4; Apo-E; Apolipoprotein E Isoform 5; LPG; Apolipoprotein E Isoform 2; Apolipoprotein E; LDLCQ5
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