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Results for "

cationic liposomes

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

2

Fluorescent Dyes

13

Biochemical Assay Reagents

1

Peptides

2

Isotope-Labeled Compounds

20

Oligonucleotides

1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112005
    DOPE
    Maximum Cited Publications
    10 Publications Verification

    Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

    		 Liposome Endogenous Metabolite Inflammation/Immunology
    DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
    DOPE
  • HY-130751
    DODAP
    1 Publications Verification

    		 Liposome Inflammation/Immunology
    DODAP is a cationic lipid utilized as the lipid component in liposomes (pKa = 5.59 in TNS binding tests). DODAP is employed for encapsulating siRNA and delivering immunostimulated chemotherapeutic agents both in vitro and in vivo. DODAP holds great promise for research in vaccines and inflammation .
    DODAP
  • HY-139200
    DOTMA
    1 Publications Verification

    		 Liposome Others
    DOTMA is a cationic lipid that has been used as a non-viral vector for gene therapy. DOTMA is used as a component of liposomes to encapsulate siRNA, microRNA, and oligonucleotides and for in vitro gene transfection. DOTMA promotes effective interaction between liposomes and cell membranes by inducing positive charge on the liposomes. DOTMA showed good gene transfection effect both in vitro and in vivo .
    DOTMA
  • HY-131119
    Dimethyldioctadecylammonium bromide

    Dioctadecyldimethylammonium bromide; DODAB

    		 Liposome Others
    Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
    Dimethyldioctadecylammonium bromide
  • HY-139298
    L319
    1 Publications Verification

    Di((Z)-Non-2-en-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate

    		 Liposome Inflammation/Immunology
    L319 is an ionizable cationic lipidoid and can be used for synthetic liposomes, from the patent WO-2011153493-A2, compound 1 .
    L319
  • HY-W590549
    Dioleyldimethylammonium chloride

    DODAC

    		 Liposome Cancer
    Dioleyldimethylammonium chloride (DODAC) is a positively charged lipid promoter with membrane-disrupting activity, which is often formulated into cationic liposomes with dioleoylphosphatidylethanolamine. Dioleyldimethylammonium chloride is used in gene transfection research; through electrostatic interactions, it effectively promotes the binding of programmable fusion vesicles to cells and induces membrane disruption. Dioleyldimethylammonium chloride is also applied in studies on L1210 leukemia and LS180 human colon cancer .
    Dioleyldimethylammonium chloride
  • HY-112766
    DPyPE

    		Liposome Others
    DPyPE is a neutral phosphatidylethanolamine lipid composed of a polyisoprene alkyl chain with two pyridine-containing phosphine ligands. DPyPE is mainly used in liposome formulations and to enhance the efficiency of gene delivery in vitro and in vivo. For example, DPyPE can be mixed with cationic lipids such as VC1052 (HY-156616) (in a 1:1 ratio) to form the vaccine adjuvant Vaxfectin (HY-142998). DPyPE assists VC1052 in binding to negatively charged pDNA to form a uniform liposome complex by regulating the fluidity and stability of the liposome membrane .
    DPyPE
  • HY-W416291
    Polyadenylic acid potassium

    Poly(A)

    		 Biochemical Assay Reagents Cancer
    Polyadenylic acid potassium, also known as Poly(A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly(A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly(A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly(A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents.
    Polyadenylic acid potassium
  • HY-144018
    18:1 EPC chloride

    		Liposome Others
    18:1 EPC chloride is a cationic alkylated phospholipid and also an egg yolk phosphatidylcholine. 18:1 EPC chloride can be used in research on liposomes and drug delivery .
    18:1 EPC chloride
  • HY-D1556
    18:1 PE CF

    1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) ammonium

    		 Fluorescent Dye Cancer
    18:1 PE CF (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium)) is a pH-sensitive fluorescent indicator. 18:1 PE CF exhibits changes in fluorescence intensity in response to pH variations and reflects the electrostatic states of cationic liposomes and lipoplexes. 18:1 PE CF supports real-time visualization of pH distribution and membrane deformation in giant unilamellar vesicles and is suitable for steady-state fluorescence testing in large unilamellar vesicle membranes. 18:1 PE CF is capable of monitoring the surface electrical potential of cationic liposomes and lipoplexes and can effectively label lipid bilayers and nanomicelles. 18:1 PE CF can be used for the research of the investigation of lung cancer (Ex = 495 nm; Em = 520 nm) .
    18:1 PE CF
  • HY-144025
    DOBAQ

    		Liposome Others
    DOBAQ, a cationic lipid, is a pH-sensitive lipid. DOBAQ can be used for liposomes applied in drug delivery .
    DOBAQ
  • HY-112763
    CLinDMA

    		Liposome Inflammation/Immunology
    CLinDMA, a cationic lipid, can cause inflammatory response. CLinDMA can be used for the synthesis LNP201. LNP201 is a liposome assembly for systemic delivery of siRNA .
    CLinDMA
  • HY-112005GL
    DOPE (GMP Like)

    Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)

    		 Liposome Endogenous Metabolite Inflammation/Immunology
    DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
    DOPE (GMP Like)
  • HY-W800783
    DSTAP chloride

    CDESA

    		 Liposome Others
    DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
    DSTAP chloride
  • HY-144021
    14:0 EPC chloride

    		Liposome Others
    14:0 EPC chloride is an acyl cationic lipid that can be used for liposomes applied in drug delivery .
    14:0 EPC chloride
  • HY-W800782
    DC-6-14

    		Liposome Others
    DC-6-14 is a cationic lipid with gene transfection activity, which can be used for the synthesis of liposomes .
    DC-6-14
  • HY-W800776
    DORI

    1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide

    		 Liposome Others
    DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .
    DORI
  • HY-153125
    DLRIE

    		Liposome Others
    DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids .
    DLRIE
  • HY-172558
    MEL-A

    		Biochemical Assay Reagents Others
    MEL-A is a glycolipid biosurfactant. MEL-A can be produced from vegetable oils by Pseudozyma yeasts. MEL-A can improve the low-temperature fluidity of biodiesel and hydrocarbon fuels. MEL-A is composed of a mixture of MEL-A isoforms with variable lengths of the fatty acid chain. MEL-A can significantly increases gene transfection by cationic liposomes via membrane fusion .
    MEL-A
  • HY-160275
    DOPE-PEG2000-Fluor 555

    		Liposome Others
    DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
    DOPE-PEG2000-Fluor 555
  • HY-168777
    Lipid 7-1

    		Liposome Others
    Lipid 7-1 is an ionizable cationic lipid that can be used for the preparation of liposomes .
    Lipid 7-1
  • HY-145797
    L343

    		Liposome Others
    L343 is an ionizable cationic lipidoid and can be used to synthetic liposomes for systemic delivery of RNAi therapeutics.
    L343
  • HY-144023
    16:0-18:1 EPC chloride

    		Liposome Others
    16:0-18:1 EPC chloride is a cationic lipid, which can be used for liposomes applied in drug delivery .
    16:0-18:1 EPC chloride
  • HY-160581
    OH-C-Chol

    		Liposome Others
    OH-C-Chol is a cationic liposome that serves as a siRNA delivery vehicle. OH-C-Chol (LP-C) and OH-NC-Chol (LP-NC)/siRNA complexes (lipoplexes) showed better performance than NP-C and NP-NC/siRNA complexes (nanocomplexes), respectively. ) greater gene silencing effect .
    OH-C-Chol
  • HY-P10968
    KT2

    		Bacterial Antibiotic Infection
    KT2 is a cationic amphipathic antibacterial peptide. KT2 can completely kill cells of E. coli O157:H7. KT2 has potent anti-biofilm activity and prevents biofilm formation of E. coli O157:H7. KT2 significantly binds to bacterial surface LPS and interacts with the lipids of liposomes with great penetration capability into bacterial cells, followed by bond to DNA and other cytoplasmic membrane .
    KT2
  • HY-112005S
    DOPE-d62

    Dioleoylphosphatidylethanolamine-d62; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-d62

    		 Isotope-Labeled Compounds Inflammation/Immunology
    DOPE-d62 (Dioleoylphosphatidylethanolamine-d62) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
    DOPE-d62
  • HY-W1130442
    DMA4-H228

    		Liposome Inflammation/Immunology Cancer
    DMA4-H228 is a highly spleen-targeted, ionizable cationic liposome. DMA4-H228 is used to prepare lipid nanoparticles (LNPs) loaded with mRNA for the delivery of mRNA in vivo .
    DMA4-H228
  • HY-W724291
    Dimethyldioctadecylammonium-d3 bromide

    Dioctadecyldimethylammonium-d3 bromide; DODAB-d3

    		 Isotope-Labeled Compounds Liposome Others
    Dimethyldioctadecylammonium-d3 bromide (Dioctadecyldimethylammonium-d3 bromide) is the deuterium labeled Dimethyldioctadecylammonium bromide (HY-131119). Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
    Dimethyldioctadecylammonium-d3 bromide

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