21 Results for "

cell-free system

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "cell-free system" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-13295
CAS No.: 42971-09-5
Purity:  99.57%
Synonyms: Ethyl apovincaminate
Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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1
1 Cited Publications
Cat. No.: HY-P702444
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC7A11; Cystine/Glutamate Transporter; Solute Carrier Family 7 Member 11; Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ system) Member 11; XCT; Uncharacterized Protein SLC7A11; Solute Carrier Family 7 (Anionic Amino Acid Transporter Light
Species:  
Source:  
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Cat. No.: HY-101893
CAS No.: 35340-49-9
Purity:  98.48%
Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.
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Cat. No.: HY-131920A
CAS No.: 28086-43-3
Synonyms: Polyuridylic acid potassium
Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates .
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Cat. No.: HY-13295R
CAS No.: 42971-09-5
Synonyms: Ethyl apovincaminate (Standard)
Vinpocetine (Standard) is the analytical standard of Vinpocetine. This product is intended for research and analytical applications. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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Cat. No.: HY-W112090
CAS No.: 72076-09-6
Synonyms: PdTFPP; 5,10,15,20-Tetrakis(pentafluorophenyl)-21H,23H-porphine palladium(II)
Target:  

Fluorescent Dye

Research Areas:  

Others

Palladium meso-tetra(pentafluorophenyl)porphyrin (PdTFPP) derives from palladium(II), acting as a fluorescence-quenched optical probe and high-performance oxygen concentration sensor with outstanding photostability and antioxidant capacity. Palladium meso-tetra(pentafluorophenyl)porphyrin exhibits reduced luminescence intensity as dissolved oxygen concentration rises. Palladium meso-tetra(pentafluorophenyl)porphyrin can be applied for real-time monitoring of live-cell respiration, hypoxic tissue imaging, and nanofibrous organic semiconductors in photodetectors for ambient oxygen detection .
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Cat. No.: HY-N15379
CAS No.: 1355-31-3
Catharine is an alkaloid found in Catharanthus roseus and can be synthesized in a cell-free system derived from Catharanthus roseus .
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Cat. No.: HY-N13880
CAS No.: 69579-74-4
Adustin, an antifungal antibiotic, is a polypeptide with translation-inhibiting activity. Adustin inhibits translation in a cell-free rabbit reticulocyte lysate system with an IC50 of 0.34 μM .
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Cat. No.: HY-B0019
CAS No.: 123040-69-7
Synonyms: (Rac)-SENS-401 free base
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .
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Cat. No.: HY-121174
CAS No.: 39723-40-5
Synonyms: Catharticin
Alaternin (Catharticin) is an anthraquinone compound with antioxidant and hepatoprotective activities. Alaternin has an inhibitory activity against hydroxyl radicals generated in a cell-free chemical system (FeSO4/H2O2) with an IC50 value of 3.05 μM. Alaternin exhibits hepatoprotective activity against Tacrine (HY-111338)-induced toxicity in human hepatic HepG2 cells with an EC50 value of 4.02 μM .
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Cat. No.: HY-13295S
CAS No.: 2734920-39-7
Vinpocetine-d5 is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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Cat. No.: HY-W777959
CAS No.: 1329611-23-5
Azasetron Hydrochloride- 13C,d3 is the deuterium and 13C-labeled Azasetron (HY-B0019). Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .
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Cat. No.: HY-145534
CAS No.: 152064-94-3
Synonyms: CAR 8:1; C8:1 Carnitine; L-Carnitine trans-2-octenoyl ester
Research Areas:  

Metabolic Disease

trans-2-Octenoyl-L-carnitine (CAR 8:1; C8:1 Carnitine; L-Carnitine trans-2-octenoyl ester) is a medium-chain monounsaturated acylcarnitine that rarely occurs in healthy humans, and it is a fatty acid oxidation-related metabolite associated with gut microbiota-host co-metabolism. trans-2-Octenoyl-L-carnitine can serve as an analytical reference standard for qualitative and quantitative detection of carnitine metabolites in scientific research, particularly in human urine samples.
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Cat. No.: HY-161093
Research Areas:  

Cancer

PROTAC BRD4 Degrader-23 is a visible light-regulated BRD4 PROTAC degrader, with DC50 values of 6871 nM and < 30 nM in the dark and under light exposure, respectively; its IC50 values are 1172 nM and 140 nM under the corresponding conditions. PROTAC BRD4 Degrader-23 shows inhibited activity in dark environments, and recovers BRD4 degradation ability upon irradiation with 405 nm visible light. PROTAC BRD4 Degrader-23 inhibits tumor cell proliferation in a visible light-dependent manner. PROTAC BRD4 Degrader-23 can be used in studies of BRD4-dependent B-cell lymphoma .
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Cat. No.: HY-101893R
CAS No.: 35340-49-9
Dihydrofluorescein diacetate (Standard) is the analytical standard of Dihydrofluorescein diacetate (HY-101893). This product is intended for research and analytical applications. Dihydrofluorescein diacetate is a fluorimetric probe mainly used for oxidative stress measurements, in both cell-free systems and cellular models.
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Cat. No.: HY-P702224
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RHD; Rhesus Blood Group Antigen CE; Prev. RH; Rhesus Blood Group D Antigen; SLC42A5; Rhesus system D Polypeptide; CD240D; Rh Blood Group, D Anitgen; DIIIc; RhD Blood Group D Antigen; RhPI; Rh Blood Group, D Antigen; RhII; Rh Blood Group CE Antigen; Rh4; R
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Cat. No.: HY-133240
CAS No.: 1109241-72-6
trans-AzoTAB is a photoresponsive potassium/sodium/calcium channel modulator and DNA-binding agent. trans-AzoTAB undergoes trans-cis isomerization driven by light, with variable polarity and DNA affinity. trans-AzoTAB also enhances voltage-gated potassium currents and inhibits sodium and calcium currents in cardiomyocytes, thereby reducing spontaneous electrical activity and excitation conduction velocity. In addition, trans-AzoTAB induces compaction and frozen conformation of λ-phage DNA, and non-sequence-dependently inhibits transcription and translation processes in the dark; its activity can be reversed and restored by visible light after activation with ultraviolet irradiation. trans-AzoTAB can serve as a probe for two-photon optical regulation of myocardial excitability, and is used to construct photoresponsive interfacial polymer structures .
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Cat. No.: HY-D3219
CAS No.: 2158197-67-0
Ctrl-CPF1 is a control dye for Copper Phosphorus Fluor 1 (CPF1), which exhibits no metal-dependent fluorescence response and shows no reactivity toward Cu + .
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Cat. No.: HY-184847
CAS No.: 2883627-66-3
Target:  

α-synuclein

Research Areas:  

Neurological Disease

α-Synuclein-IN-25 is a quinone-acid hybrid and also an α-synuclein aggregation inhibitor with an IC50 of 3.0 μM. α-Synuclein-IN-25 dissociates preformed α-Syn aggregates, inhibits their re-aggregation, scavenges reactive oxygen species, and reduces the formation of α-Syn inclusions in neuronal cells. α-Synuclein-IN-25 can be used in the research of Parkinson's disease .
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Cat. No.: HY-D3496
Synonyms: BODIPY 576/589 Succinimidyl ester
BODIPY 576/589 NHS ester (BODIPY 576/589 Succinimidyl ester) is an active fluorophore containing the BODIPY 576/589 fluorophore and an NHS ester. BODIPY 576/589 NHS ester can covalently couple red fluorescence to biomolecules containing primary amines (-NH2), such as proteins, antibodies, peptides, and oligonucleotides. BODIPY 576/589 NHS ester can also be used to prepare BODIPY 576/589-Met-tRNAfMet to achieve N-terminal co-translational labeling of nascent proteins (Ex/Em = 576/589 nm) .
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