123040-69-7
Chemical Structure
Azasetron
Synonym(s): (Rac)-SENS-401 free base
- CAS No.: 123040-69-7
- Formula:C17H20ClN3O3
- Molecular Weight:349.81
IUPAC Name: 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide
InChIKey: WUKZPHOXUVCQOR-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=CC2=C1OCC(N2C)=O)NC3CN4CCC3CC4
Biological Activity: Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems[1].
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Azasetron | Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems. | |||||||||||||||||||||
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Azasetron-d3 hydrochloride | Azasetron-d3 (hydrochloride) is the deuterium labeled Azasetron hydrochloride. | |||||||||||||||||||||
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Azasetron Hydrochloride-13C,d3 | Azasetron Hydrochloride-13C,d3 is the deuterium and 13C-labeled Azasetron (HY-B0019). Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems. | |||||||||||||||||||||
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